Results 151 to 160 of about 50,846 (317)
Aryl Hydrocarbon Receptor in Health and Disease
MedComm, Volume 6, Issue 11, November 2025.Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li +11 more
wiley +1 more source
Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.Vasculature‐Associated Lymphoid Tissue (VALT) is a significant tertiary lymphoid tissue that contributes to kidney inflammation and has not yet been identified in ruminants. Our study revealed that VALT in goats consists of typical immune cells, including macrophages, T cells, B cells and high endothelial venules.
Md. Abdul Masum +2 more
wiley +1 more source
British Journal of Pharmacology, Volume 182, Issue 21, Page 5355-5377, November 2025.Background and purpose Diabetic nephropathy (DN) is a common complication of diabetes. Current treatments include renin‐angiotensin‐aldosterone system (RAAS) blockers and sodium‐glucose co‐transporter 2 (SGLT2) inhibitors. The cannabinoid CB1 receptor is a potential therapeutic target.
Océane Pointeau +20 more
wiley +1 more source
Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis [PDF]
, 2001 Dontscho Kerjaschki
openalex +2 more sources
Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate [PDF]
, 2000 Bryan L. Wharram +9 more
openalex +1 more source
Histidine‐Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review
Obesity Reviews, Volume 26, Issue 11, November 2025.ABSTRACT Background Histidine‐containing dipeptides (HCDs) have been reported to have anti‐inflammatory and antidiabetic properties. Yet, no previous reviews have examined the impact of HCDs on Type 2 diabetes (T2D) risk factors (e.g., obesity) and progression (e.g., microvascular and macrovascular complications).
Saeede Saadati +10 more
wiley +1 more source
Angiotensin II increases the intracellular calcium activity in podocytes of the intact glomerulus [PDF]
, 2000 Roland Nitschke +6 more
openalex +1 more source
New Ways of Thinking about Proteinuria and Progression of Renal Damage [PDF]
, 2010 Turner, Neil, Zhou, Y. S.
core +1 more source
Physiological Reports, Volume 13, Issue 21, November 2025.Certain ligands of pattern recognition receptors can induce a rapid increase in albumin permeability across a podocyte monolayer that can be seen in 1 h, but activation of TRPC6 for up to 24 h does not mimick this process. However, continuous TRPC6 activation for 24 h results in nephrin ectodomain shedding that calcineurin activation and ...
Eun Young Kim, Stuart E. Dryer
wiley +1 more source