Results 191 to 200 of about 50,846 (317)

Tubular Injury in Diabetic Kidney Disease: Early Diagnosis and Intervention Strategies

Diabetes/Metabolism Research and Reviews, Volume 41, Issue 7, October 2025.
ABSTRACT Diabetic kidney disease (DKD) is the most severe complication of diabetes mellitus and has poor prognosis, often progressing to end‐stage renal disease, causing substantial morbidity and mortality globally. While the pathogenesis of DKD has been extensively characterised, including glomerular hyperfiltration, podocyte injury, and ...
Yi Lv, Chen Ye, Zixi Li, Jiajia Ye, Huanhuan Cao, Chun Zhang, Huajun Jiang, Yumei Wang   +7 more
wiley   +1 more source

Amino acid transport in podocytes

, 2000
Joachim Gloy, Steffen Reitinger, Karl-Georg Fischer, Rainer Schreiber, Anissa Boucherot, Karl Kunzelmann, Peter Mündel, Hermann Pavenstädt   +7 more
openalex   +1 more source

Multi‐Target Modulation of Polyphenols in Diabetic Kidney Disease Therapeutics: A Comprehensive Review

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
This review shows evidence from preclinical and clinical studies, supporting the therapeutic potential of polyphenols for diabetic kidney disease (DKD). This is due to their diverse bioactive properties and ability to intervene in intricate mechanisms of the disease.
Esienanwan E. Efiong, Emmanuel Effa, Esther Peters, Ochuko L. Erukainure, Peter U. Amadi, Joshua Onyeka Ikebuiro, Sapna Sharma, Christoph Schmaderer, Kathrin Maedler, Emmy Tuenter, Harald Grallert   +10 more
wiley   +1 more source

Diminution of Podocyte Anionic Sites in Drug-Induced Proteinuric Rats.

, 2000
Akihito Shimoi, Tsuyoshi Harada, Mitsutoshi Watanabe   +2 more
openalex   +2 more sources

Apoptosis in podocytes induced by TGF-β and Smad7 [PDF]

, 2001
Mario Schiffer, Markus Bitzer, Ian S.D. Roberts, Jeffrey B. Kopp, Peter ten Dijke, Peter Mündel, Erwin P. Böttinger   +6 more
openalex   +1 more source

Hypoxia-inducible factor 2α overexpression in podocytes ameliorates lipid metabolism disorders in diabetic kidney disease by inhibiting S1P. [PDF]

Ren Fail
Yang X, Wang Q, Nie H, Wang M, Wang Y, Li S, Liu Q, Liu G.   +7 more
europepmc   +1 more source

Selected miRNAs in Urinary Extracellular Vesicles Show Promise for Early and Specific Diagnostics of Diabetic Kidney Disease

Journal of Extracellular Biology, Volume 4, Issue 10, October 2025.
Abstract Diabetic kidney disease (DKD) is a health burden that lacks specific and early diagnostic biomarkers. For their discovery, we sequenced urinary extracellular vesicle miRNAs in a type 1 diabetes cohort of males with and without DKD. The results were replicated by sequencing or qPCR in two independent cohorts and six published datasets ...
Karina Barreiro, Jenni Karttunen, Erkka Valo, Essi Viippola, Ileana Quintero, Annemari Käräjämäki, Antti Rannikko, Harry Holthöfer, Andrea Ganna, Niina Sandholm, Lena M. Thorn, Per‐Henrik Groop, Tiinamaija Tuomi, Om Prakash Dwivedi, Maija Puhka   +14 more
wiley   +1 more source

LncRNA ENST00000532153.1 alleviates podocyte injury by inhibiting PARP1-mediated PARylation of ATF3 in diabetic kidney disease. [PDF]

Cell Mol Life Sci
Yu Q, Yang M, Lu S, Su H, Liu Y, Zhang X, Fan X, Lv Z, Wang R.   +8 more
europepmc   +1 more source

Podocyte-Associated Molecules in Puromycin Aminonucleoside Nephrosis of the Rat [PDF]

, 2002
Pauliina Luimula, Niclas Sandström, Dmitry S. Novikov, Harry Holthöfer   +3 more
openalex   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin, Chujun Ni, Haiyang Jiang, Huan Yang, Liting Deng, Peizhao Liu, Xuanheng Li, Yilong Yu, Weijie Li, Runnan Wang, Bo Liao, Jiaqi Kang, Juanhan Liu, Xiuwen Wu, Jianan Ren, Yun Zhao   +15 more
wiley   +1 more source