Results 201 to 210 of about 68,048 (352)

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency [PDF]

, 2017
Connolly, Anne M, Cooper, Megan A, Dharnidharka, Vikas R, et al,, Willing, Marcia C   +4 more
core   +2 more sources

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu, Xiao‐Mei Wu, Yan Hu, Xiao‐Lan Bian, Ya‐Qin Wang, Qiong‐Ni Zhu   +5 more
wiley   +1 more source

Counting glomeruli in human kidney specimens using ex vivo MRI without contrast agents

Magnetic Resonance in Medicine, Volume 94, Issue 6, Page 2519-2528, December 2025.
Abstract Purpose The total number of glomeruli is an important indicator of kidney function and susceptibility to disease. Glomeruli, however, are difficult to image using MRI without contrast enhancement. For this reason, previous studies have used cationic ferritin as a contrast agent to detect glomeruli in ex vivo and in vivo perfused kidneys.
Nyoman D. Kurniawan, Aurel J. Amar, Luise A. Cullen‐McEwen, Alexander N. Combes, Raeesah Hayatudin, Andrew J. Kassianos, Jiaxin Du, Sarah E. Gazzard, Helen G. Healy, Wendy E. Hoy, John F. Bertram, David C. Reutens   +11 more
wiley   +1 more source

Cell biology of diabetic nephropathy: Roles of endothelial cells, tubulointerstitial cells and podocytes [PDF]

, 2014
Yoshiro Maezawa, Minoru Takemoto, Koutaro Yokote   +2 more
openalex   +1 more source

Continuous Exposure to Environmental Endocrine Disruptors on the Prognosis of Children With Nephritis: An Observational Cohort Study

Reproductive, Female and Child Health, Volume 4, Issue 4, December 2025.
ABSTRACT Objective Explore the impact of partial urinary environmental endocrine disruptors (EEDs) on the pathogenesis and renal function in paediatric patients diagnosed with Henoch‐Schönlein purpura nephritis (HSPN). Methods This was an observational cohort study.
Hongjun Peng, Shuting Yu, Yaning Zheng, Taiyu Song, Jinya Wang, Xianguo Ren, Guangling Liu   +6 more
wiley   +1 more source

A human stem cell-derived model reveals pathologic extracellular matrix remodeling in diabetic podocyte injury

Matrix Biology Plus
Diabetic nephropathy results from chronic (or uncontrolled) hyperglycemia and is the leading cause of kidney failure. The kidney’s glomerular podocytes are highly susceptible to diabetic injury and subsequent non-reversible degeneration.
Yasmin Roye, Carmen Miller, Titilola D. Kalejaiye, Samira Musah   +3 more
doaj   +1 more source

Disruption of Myosin 1e Promotes Podocyte Injury [PDF]

, 2008
Mira Krendel, Sangwon V. Kim, Tim Willinger, Tong Wang, Michael Kashgarian, Richard A. Flavell, Mark S. Mooseker   +6 more
openalex   +1 more source

Antibacterial and Antibiotic‐Enhancing Activity of 3‐Hydroxy‐4‐methoxycinnamic Acid: Experimental Data and In Silico Predictions

ChemistrySelect, Volume 10, Issue 47, December 15, 2025.
ABSTRACT The growing bacterial resistance, driven by the inappropriate use of antibiotics, poses a global health threat and demands new therapeutic strategies. Natural phenolic compounds, such as 3‐hydroxy‐4‐methoxycinnamic acid (3H4MCA), stand out due to their antimicrobial and antioxidant properties, showing potential in combating resistant pathogens.
José Thyálisson da Costa Silva, Viviane Bezerra da Silva, Guilherme Fernandes Teixeira, Carlos Alonso Leite dos Santos, Antonia Adeublena de Araujo Monteiro, Janaína Esmeraldo Rocha, Ewerton Yago de Sousa Rodrigues, Rafael Pereira da Cruz, Isaac Moura Araújo, Adrielle Rodrigues Costa, Cicera Laura Roque Paulo, Irwin Rose Alencar de Menezes, Maria Flaviana Bezerra Morais‐Braga, José Maria Barbosa‐Filho, Saulo Almeida de Menezes, Henrique Douglas Melo Coutinho, José Weverton Almeida‐Bezerra   +16 more
wiley   +1 more source

CD2-associated Protein (CD2AP) Expression in Podocytes Rescues Lethality of CD2AP Deficiency [PDF]

, 2005
James A. Grunkemeyer, Christopher Kwoh, Tobias B. Huber, Andréy S. Shaw   +3 more
openalex   +1 more source

Normal and Dysregulated Sphingolipid Metabolism: Contributions to Podocyte Injury and Beyond [PDF]

Matthew Tolerico, Sandra Merscher, Alessia Fornoni   +2 more
openalex   +1 more source