Results 41 to 50 of about 710 (162)
The markers of renal involvement in Anderson-Fabry disease are defects of urine concentration, presence of cells with lipid cytoplasmatic inclusions (mulberry bodies) and podocyturia. The loss of urine concentrating capacity is not easy to detect and the
Sandro Feriozzi, Mario Mangeri
doaj +1 more source
Urinary podocin level as a predictor of diabetic kidney disease [PDF]
Background: Albuminuria showed to be a deteriorating condition in diabetic kidney disease (DKD) associated with high morbidity and mortality. A need for a novel marker for early detection of DKD development and progression becomes mandating.
Abdelbassit ElShaarawy +4 more
doaj +1 more source
Resumen: Introducción: En el síndrome nefrótico, la podocituria aumentada acompaña a la proteinuria patológica. El tratamiento con enalapril, losartán y amiloride podría reducir ambas variables.
Miguel Liern +3 more
doaj +1 more source
Podocyturia: why it may have added value in rare diseases. [PDF]
Fabry disease is an inherited lysosomal disease in which defects in the GLA gene lead to α-galactosidase-A deficiency, and accumulation of glycosphingolipids, including lyso-Gb3, a podocyte stressor. Therapy is available as enzyme replacement therapy and, for some patients, the chaperone migalastat.
Sanchez-Niño MD +4 more
europepmc +5 more sources
Persistent urinary podocyte loss following preeclampsia may reflect subclinical renal injury. [PDF]
Studies have shown that podocyturia, i.e., urinary loss of viable podocytes (glomerular epithelial cells), is associated with proteinuria in preeclampsia. We postulated that urinary podocyte loss may persist after preeclamptic pregnancies, thus resulting
Wendy M White +9 more
doaj +1 more source
Biomarkers for diagnosis of pre-eclampsia and endometriosis [PDF]
Gynecological disorders are leading public health problems in developing countries with substantial impact on women's quality of life. Significant proportion of maternal mortality and reproductive morbidity is attributed to misdiagnosis ...
Ali, Amjad +6 more
core +1 more source
Study of Urinary WT1 Positive Cells as a Biomarker for Detection of Glomerular Diseases
Introduction: Glomerular diseases form a large part of the morbidity and mortality associated with kidney diseases. Podocyte injury and loss is implicated in a number of these diseases.
Jayesh Saha , Ranjana Solanki , Madan Solanki , Utkarsh Sharma , Suman Meena , Vijaya S Devi, Poonam Arora, Gurvi Chauhan
doaj +1 more source
Renal Evaluation in Women with Preeclampsia [PDF]
Background/Aims: Preeclampsia (PE) is a cause of glomerulopathy worldwide. Urinary retinol-binding protein (RBP) is a marker of proximal tubular dysfunction, albuminuria is an endothelial injury marker, urine protein:creatinine ratio (PCR) may have a ...
Facca, T.A. +6 more
core +3 more sources
Metabolic progression to clinical phenotype in classic Fabry disease [PDF]
BACKGROUND: Fabry disease is an X-linked lysosomal storage disorder due to α-galactosidase A (α-Gal A) deficiency. Clinical onset of Fabry disease is preceded by significant storage of globotriaosylceramide (Gb3) and related glycosphingolipids, but the ...
Biamino, Elisa +5 more
core +3 more sources
Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]
Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
core +1 more source

