Results 91 to 100 of about 19,338 (290)

Podoplanin—a novel marker in oral carcinogenesis

Tumor Biology, 2014
Podoplanin, a transmembrane sialoglycoprotein, is a specific marker for lymphatic endothelial cells which in recent years has gained prominent notoriety for its role in tumor progression and metastasis. It is an extensively studied biomarker for predictive assessment of malignant transformation as well as biologic behavior in both human precancer and ...
Shilpa Nilesh Patel, Samapika Routray, Shwetha V. Kumar, Jigna Pathak, Niharika Swain   +4 more
openaire   +3 more sources

CLEC-2 Prevents Accumulation and Retention of Inflammatory Macrophages During Murine Peritonitis

Frontiers in Immunology, 2021
Platelets play a key role in the development, progression and resolution of the inflammatory response during sterile inflammation and infection, although the mechanism is not well understood.
Joshua H. Bourne, Nonantzin Beristain-Covarrubias, Malou Zuidscherwoude, Malou Zuidscherwoude, Joana Campos, Ying Di, Evelyn Garlick, Evelyn Garlick, Martina Colicchia, Lauren V. Terry, Steven G. Thomas, Steven G. Thomas, Alexander Brill, Alexander Brill, Jagadeesh Bayry, Jagadeesh Bayry, Steve P. Watson, Steve P. Watson, Julie Rayes, Julie Rayes   +19 more
doaj   +1 more source

Novel knock‐in mouse model for the evaluation of the therapeutic efficacy and toxicity of human podoplanin–targeting agents

Cancer Science, 2021
Podoplanin is a key molecule for enhancing tumor‐induced platelet aggregation. Podoplanin interacts with CLEC‐2 on platelets via PLatelet Aggregation–inducing domains (PLAGs). Among our generated antibodies, those targeting the fourth PLAG domain (PLAG4)
Takao Ukaji, Ai Takemoto, Harumi Shibata, M. Kakino, S. Takagi, Ryohei Katayama, N. Fujita   +6 more
semanticscholar   +1 more source

Quantitative Histomorphometry of the Healthy Peritoneum [PDF]

, 2016
The peritoneum plays an essential role in preventing abdominal frictions and adhesions and can be utilized as a dialysis membrane. Its physiological ultrastructure, however, has not yet been studied systematically.
A Dart, AH Bouts, AM Zurowska, AW de Boer, B Rippe, BA Warady, BV Robinson, CP Schmitt, F Schneble, H Tenckhoff, J Latus, J Latus, J Loureiro, J Stachowska-Pietka, JD Williams, K Kawanishi, KD Nolph, LP Kihm, M Flessner, M Zareie, MF Flessner, N Di Paolo, O Devuyst, R Feneberg, RT Krediet, TJ Cole, YT Chen   +26 more
core   +4 more sources

Podoplanin is a useful prognostic marker and indicates better differentiation in lung squamous cell cancer patients? A systematic review and meta-analysis

BMC Cancer, 2020
Background The CSC (cancer stem cell) markers often indicate poor prognosis and more cell invasion or migration of cancer patients. Podoplanin was assumed as a candidate CSC marker and predict poor prognosis among squamous cancers.
Liya Hu, Peng Zhang, Qi Mei, Wei Sun, Lei Zhou, Tiejun Yin   +5 more
doaj   +1 more source

Pathologic diagnosis of malignant mesothelioma: chronological prospect and advent of recommendations and guidelines [PDF]

, 2015
Malignant mesothelioma is rare and difficult to diagnose. Its identification depends upon pathological investigation (cyto-histological assessment and immunohistochemistry) supported by clinical and radiological evidence.
Ascoli, Valeria
core   +2 more sources

Robotic Resection of Parapharyngeal Follicular Dendritic Cell Sarcoma With Castleman Disease

The Laryngoscope, EarlyView.
Parapharyngeal follicular dendritic cell sarcoma (FDCS) is rare and may occur with Castleman disease. We describe the successful transoral robotic resection of a parapharyngeal FDCS associated with Castleman disease, highlighting the role of the robotic approach in achieving tissue diagnosis and definitive treatment.
Lily Huang, Aman M. Patel, Timothy Chao, Ryan M. Carey   +3 more
wiley   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources

Human skin‐derived micronized acellular dermal matrix modulates angiogenesis to enhance tissue reconstruction

VIEW, EarlyView.
Angiogenesis is an essential process in tissue regeneration, as it prevents complications such as necrosis, inflammation, and fibrosis. mADM decellularized by the supercritical carbon dioxide method exhibits high preservation of the extracellular matrix and various growth factors.
Hyo‐Jin Kim, Won‐Hong Min, Soohyun Kim, Duri Lee, Jin Woo Bae, Yongwoo Shin, Kyusup An, Bo‐Gyeong Seo, Won‐bin Jo, Kwang Dong Kim, Jiyun Yoo, Hyuk‐Kwon Kwon, Jeong‐Hyung Lee, Ki Yong Hong, Cheol Hwangbo   +14 more
wiley   +1 more source

Evaluation of Podoplanin in Oral Leukoplakia and Oral Squamous Cell Carcinoma

Scientifica, 2015
Background. Recent studies have demonstrated that podoplanin was expressed in some dysplastic lesions adjacent to primary oral cancers suggesting that podoplanin expression may occur in early oral tumorigenesis and lymphangiogenesis and therefore is ...
Ashok Patil, Kishor Patil, Suyog Tupsakhare, Mahesh Gabhane, Shrikant Sonune, Shilpa Kandalgaonkar   +5 more
doaj   +1 more source