Results 171 to 180 of about 11,879 (214)

Enhanced expression of podoplanin in ameloblastomas

Journal of Oral Pathology & Medicine, 2010
Podoplanin, a mucin-type transmembrane glycoprotein, is specifically expressed by lymphatic but not blood vascular endothelial cells, and is also widely expressed in various specialized cell types throughout the body. Recent studies have demonstrated that it mediates a pathway leading to collective cell migration and invasion in vivo and in vitro.
Patricia, González-Alva, Akio, Tanaka, Yuka, Oku, Yuji, Miyazaki, Eri, Okamoto, Masahiro, Fujinami, Noriaki, Yoshida, Kentaro, Kikuchi, Fumio, Ide, Hideaki, Sakashita, Kaoru, Kusama   +10 more
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Detection of Alpaca Podoplanin by Immunohistochemistry Using the Antibovine Podoplanin Monoclonal Antibody PMab-44

Monoclonal Antibodies in Immunodiagnosis & Immunotherapy, 2018
Podoplanin (PDPN) is expressed in type I alveolar cells of the lungs, lymphatic endothelial cells, and podocytes of the kidneys, and induces platelet aggregation through the C-type lectin-like receptor-2. PDPNs of various animal species have been characterized using specific anti-PDPN monoclonal antibodies (mAbs).
Yukinari, Kato, Shinji, Yamada, Shunsuke, Itai, Satoru, Konnai, Atsushi, Kobayashi, Mika K, Kaneko   +5 more
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Anti-Bovine Podoplanin Monoclonal Antibody PMab-44 Detects Goat Podoplanin in Immunohistochemistry

Monoclonal Antibodies in Immunodiagnosis & Immunotherapy, 2019
Podoplanin (PDPN) is expressed in type I alveolar cells, kidney podocytes, and lymphatic endothelial cells. We have characterized the PDPNs of various animal species using specific anti-PDPN monoclonal antibodies (mAbs). In this study, we investigated whether these anti-PDPN mAbs cross-react with goat PDPN (gPDPN).
Shinji, Yamada, Mika K, Kaneko, Yoshikazu, Furusawa, Shunsuke, Itai, Masato, Sano, Takuro, Nakamura, Miyuki, Yanaka, Saori, Handa, Kayo, Hisamatsu, Yoshimi, Nakamura, Masanori, Koyanagi, Masato, Fukui, Hiroyuki, Harada, Yukinari, Kato   +13 more
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Immunohistochemical Detection of Sheep Podoplanin Using an Antibovine Podoplanin Monoclonal Antibody PMab-44

Monoclonal Antibodies in Immunodiagnosis & Immunotherapy, 2018
Podoplanin (PDPN) obtained from various animal species has been characterized using specific anti-PDPN monoclonal antibodies (mAbs), namely, PMab-1, PMab-2, PMab-32, PMab-38, PMab-44, and PMab-52 against mouse, rat, rabbit, dog, bovine, and cat PDPN, respectively.
Yukinari, Kato, Shinji, Yamada, Shunsuke, Itai, Atsushi, Kobayashi, Satoru, Konnai, Mika K, Kaneko   +5 more
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Detection of Tiger Podoplanin Using the Anti-Cat Podoplanin Monoclonal Antibody PMab-52

Monoclonal Antibodies in Immunodiagnosis & Immunotherapy, 2018
Podoplanin (PDPN) is expressed in type I alveolar cells of lung but not in type II alveolar cells. PDPN is also known as a specific lymphatic endothelial cell marker because PDPN is not expressed in vascular endothelial cells. PDPNs of several animals have been characterized using specific anti-PDPN monoclonal antibodies (mAbs): PMab-1, PMab-2, PMab-32,
Shinji, Yamada, Shunsuke, Itai, Yoshikazu, Furusawa, Masato, Sano, Takuro, Nakamura, Miyuki, Yanaka, Saori, Handa, Kayo, Hisamatsu, Yoshimi, Nakamura, Masato, Fukui, Hiroyuki, Harada, Takuya, Mizuno, Yusuke, Sakai, Satoshi, Ogasawara, Takeshi, Murata, Hiroaki, Uchida, Hideaki, Tahara, Mika K, Kaneko, Yukinari, Kato   +18 more
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Expression of podoplanin in the mouse salivary glands

Archives of Oral Biology, 2008
Podoplanin is one of the most highly expressed lymphatic-specific genes. Here, we report the distribution of cells expressing podoplanin in mouse salivary glands.We immunohistochemically investigated the distribution of cells expressing podoplanin in mouse major salivary glands by laser-scanning microscopy.
Minoru, Hata, Takeshi, Ueki, Atsuko, Sato, Hiroshi, Kojima, Yoshihiko, Sawa   +4 more
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Expression of podoplanin and prognosis in oropharyngeal cancer

European Archives of Oto-Rhino-Laryngology, 2014
It has been shown that podoplanin expression is associated with carcinoma of the aerodigestive tract. Recent studies indicate that podoplanin may serve as a prognostic biomarker in oral carcinoma. In order to provide evidence on the role of podoplanin in oropharyngeal squamous cell carcinoma, we evaluated the prognostic impact of podoplanin in these ...
Simon F, Preuss, Andreas, Anagiotos, Inga M C, Seuthe, Uta, Drebber, Inga, Wedemeyer, Matthias, Kreppel, Robert, Semrau, Guy D, Eslick, Jens Peter, Klussmann, Christian U, Huebbers   +9 more
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Src and podoplanin forge a path to destruction

Drug Discovery Today, 2019
Cancer and arthritis present an enormous challenge to society. They share pathogenic pathways that involve extracellular matrix degradation, tissue invasion, and inflammation. Most cancer and arthritis treatments affect normal cell function to cause significant adverse effects in patients. Specific pathways that promote cancer and arthritis progression
Harini Krishnan, W. Todd Miller, Francisco J. Blanco, Gary S. Goldberg   +3 more
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The role of podoplanin in cancer-associated thrombosis

Thrombosis Research, 2018
Venous thromboembolism (VTE) is a frequent and life-threatening complication in patients with cancer. The underlying mechanisms of cancer-associated VTE are still not completely understood. However, emerging studies indicate that the mechanisms differ across tumor types.
Pegah, Mir Seyed Nazari, Julia, Riedl, Ingrid, Pabinger, Cihan, Ay   +3 more
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Podoplanin: A Novel Diagnostic Immunohistochemical Marker

Advances in Anatomic Pathology, 2006
Podoplanin is a transmembrane mucoprotein recognized by the recently commercially available D2-40 monoclonal antibody. Recent investigations have shown that podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Podoplanin has also
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