Results 141 to 150 of about 504,749 (254)
Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Zhi Xu +9 more
wiley +2 more sources
Understanding the interplay between urban segregation and accessibility to services with network analysis. [PDF]
Lai M +5 more
europepmc +1 more source
Abstract Background Strategies to optimise bowel function before stoma reversal surgery (SRS) are needed to improve postoperative outcomes. Efferent bowel stimulation (EBS) prior to stoma closure has been proposed as a potential strategy to reduce postoperative ileus (POI) incidence and improve the patient's postoperative course.
Jorge Arredondo +76 more
wiley +1 more source
A bidirectional 2-sample Mendelian randomization study of depressed mood and premature ovarian insufficiency. [PDF]
Chen K +5 more
europepmc +1 more source
ABSTRACT Previous research suggests that the development of lateralisation throughout childhood might be related to individual differences in cognitive ability, but evidence from early childhood is lacking. The current study aimed to determine if there is a relationship between patterns of language and visuospatial lateralisation and cognitive ability ...
Josephine E. Quin‐Conroy +2 more
wiley +1 more source
Postoperative Ileus After Rectal Cancer Surgery: Assessing Incidence, Severity, and Impact Across Open, Laparoscopic, and Robotic Approaches. [PDF]
Goldenshluger M +9 more
europepmc +1 more source
ABSTRACT Aim To synthesise evidence on the impact of pre‐ and post‐loss family support interventions on bereavement outcomes and families' perceptions of their usefulness and benefits in specialist palliative care. Design A rapid mixed‐methods systematic review drawing on JBI and Cochrane guidance.
Torsten Schwalbach +3 more
wiley +1 more source
Nanomotor-Driven Extracellular Vesicles With Effective Tissue Penetration for Targeted Therapy of Primary Ovarian Insufficiency. [PDF]
Mu Y +7 more
europepmc +1 more source
ABSTRACT Primary ovarian insufficiency (POI) is a genetically heterogeneous disorder characterised by cessation of menstruation before the age of 40 years with elevated levels of follicle‐stimulating hormone. Germline variants in the MSH5 gene cause POI. In this study, we investigated a Han Chinese family with POI.
Bin Mao +9 more
wiley +1 more source

