Results 141 to 150 of about 107,031 (277)
AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley +1 more source
Large Deviations of the Giant Component in Scale‐Free Inhomogeneous Random Graphs
ABSTRACT We study large deviations of the size of the largest connected component in a general class of inhomogeneous random graphs with iid weights, parametrized so that the degree distribution is regularly varying. We derive a large‐deviation principle with logarithmic speed: the rare event that the largest component contains linearly more vertices ...
Joost Jorritsma, Bert Zwart
wiley +1 more source
ABSTRACT This study analyzes the architecture of the beyond 5G‐NTN (Non‐terrestrial Network) integrated network and presents the technical, legal, and regulatory challenges and considerations for expanding the Artificial Intelligence of Things (AIoT) ecosystem.
Byung Woon Kim, Ga Eun Choi
wiley +1 more source
Watanabe et al. (2003) show that the temperature of the deep water in the northern part of East/Japan Sea (EJS) oscillates with about 15 year cycle as the volume transport of the Tsushima warm current (TWC) reported by Takikawa and Yoon (2005).
박영규
core
Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies
ABSTRACT The complexity of transition of pediatric patients to adult care is well recognized, with a multidisciplinary approach widely agreed to be essential. Despite extensive existing literature in this area, practical guidance as to the management of specific medical aspects and how to address these with patients and families is lacking, with little
Margaret Zacharin, Quynh‐Nhu Nguyen
wiley +1 more source
Resumo Objetivo Estabelecer uma descrição geral das pessoas com paralisia cerebral (PC) no Brasil, incluindo a epidemiologia, características clínicas, funcionalidade e acesso à reabilitação e equipamentos, pela perspectiva da Classificação Internacional de Funcionalidade, Incapacidade e Saúde (CIF), utilizando dados preliminares do Registro Brasileiro
Hércules Ribeiro Leite +10 more
wiley +1 more source
ABSTRACT Purpose Type 1 diabetes is a chronic autoimmune disease characterised by progressive pancreatic β‐cell destruction and the early appearance of islet autoantibodies (islet‐AAb) during the pre‐symptomatic phases. Given the growing interest in screening and prevention of type 1 diabetes, this study aimed to assess the prevalence of pancreatic ...
Giuseppe Bellastella +11 more
wiley +1 more source
Large-scale analysis of FMR1 CGG repeat length and risk of premature ovarian insufficiency in over 92 000 women. [PDF]
Morbey EJ +7 more
europepmc +1 more source
La regolamentazione dell'attività assicurativa
Il contributo fornisce un quadro aggiornato del sistema normativo e di vigilanza dell’attività assicurativa, secondo il Codice delle assicurazioni private (D. Lgs.
Antonella Cappiello, Luca Di Poi
core

