Results 71 to 80 of about 130,774 (227)

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik   +3 more
wiley   +1 more source

Dynamic Recommendation of POI Sequence Responding to Historical Trajectory

open access: yesISPRS International Journal of Geo-Information, 2019
Point-of-Interest (POI) recommendation is attracting the increasing attention of researchers because of the rapid development of Location-based Social Networks (LBSNs) in recent years.
Jianfeng Huang   +3 more
doaj   +1 more source

Fermat hypersurfaces and subcanonical curves

open access: yes, 2011
We extend the classical Enriques–Petri theorem to s-subcanonical projectively normal curves, proving that such a curve is (s+2)-gonal if and only if it is contained in a surface of minimal degree.
FRANCESCO ZUCCONI   +3 more
core   +1 more source

Stair‐Climbing Wheelchairs for Enhanced Mobility: A Comprehensive Review of Fundamental Mechanisms, Design Concepts, and Performance Analysis

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT People with physical disabilities face significant mobility challenges while climbing uneven surfaces and staircases. In these circumstances, traditional wheelchairs do not provide stable, safely controlled mobility, underscoring the importance of building superior stair‐climbing wheelchairs for both medical and infrastructure purposes.
Gopisetti Manikanta   +10 more
wiley   +1 more source

Congruences of lines with one-dimensional focal locus

open access: yes, 2004
In this article we obtain the classification of the congruences of lines with one-dimensional focal locus.
DE POI, Pietro
core   +1 more source

On congruences of linear spaces of order one [PDF]

open access: yes, 2007
After presenting the main notions and results about congruences of k-planes, we dwell upon congruences of lines, mainly of order one. We survey the classification results in the projective spaces of dimension 3 and 4, which are almost complete, and the ...
MEZZETTI E., DE POI, Pietro
core   +2 more sources

La vida en las plantas acuáticas y palustres: La diversidad de invertebrados del Iberá

open access: yes, 2017
Los diferentes rasgos morfológicos de las plantas acuáticas estructuran el hábitat para los ensambles de invertebrados que cohabitan una misma laguna. La vegetación, además, es utilizada por esos animales como alimento cuando está viva o después de su ...
Carnevali, Romina Patricia   +2 more
core   +1 more source

High‐Speed Rail and Spatial Equity: Unpacking the Sustainability Paradox of Land Use and Fiscal Pressure in County‐Level Cities

open access: yesSustainable Development, EarlyView.
ABSTRACT Infrastructure‐led development in rapidly urbanizing economies often generates accessibility gains that fail to translate into balanced urban outcomes, particularly when local fiscal institutions redirect those gains toward revenue‐generating land uses. Filling this gap, especially in fiscally constrained county‐level cities where land finance
Ming Xie, Xiaoxiao Liao, Zhenlin Xie
wiley   +1 more source

On varieties with higher osculating defect [PDF]

open access: yes, 2013
In this paper, using the method of moving frames, we generalise some of Terracini's results on varieties with tangent defect. In particular, we characterise varieties with higher order osculating defect in terms of Jacobians of higher fundamental forms ...
P. De Poi   +5 more
core   +1 more source

Epilepsy surgery through a reproductive lifespan lens

open access: yes
Epilepsia, EarlyView.
Aisha A. Abdulrazaq   +2 more
wiley   +1 more source

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