Results 61 to 70 of about 107,031 (277)

Biallelic Germline Inactivation of HROB Causes Primary Gonadal Insufficiency and is Potentially Associated with Colonic Polyposis Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The Homologous Recombination Factor With OB‐Fold (HROB) plays a role in homologous recombination and DNA replication, where it enhances the MCM8‐MCM9 helicase complex activity. Recent findings link biallelic germline HROB variants to primary gonadal insufficiency (hypergonadotropic hypogonadism), a phenotype also associated with MCM8/MCM9 ...
Noah C. Helderman, Carli M. Tops, Jelmer Legebeke, Ting Yang, Marcos Díaz Gay, Diantha Terlouw, Lisa E. E. L. O. Lashley, Stefan Aretz, Anna K. Sommer, Mariona Terradas, Laura Valle, Richarda M. de Voer, Ludmil B. Alexandrov, Hans Morreau, Tom van Wezel, Maartje Nielsen   +15 more
wiley   +1 more source

Impact of Natural Fermentation on Mineral Composition, Resistant and Non-Resistant Starches, Microbial Diversity, and Global Metabolite Profiles in Commercial Poi from Hawai‘i

Metabolites
Background/Objectives: Taro (Colocasia esculenta L.) is a nutritionally rich and historically significant crop widely consumed in tropical and subtropical regions.
Nyan Stillwell, Vedbar S. Khadka, Pratibha V. Nerurkar   +2 more
doaj   +1 more source

On first order congruences of lines of P^4 with a fundamental curve

, 2001
We discuss projective families of lines of P^n, and in particular congruences of order one. After giving general results, we obtain a complete classification of the case of P^4 in which there is a fundamental ...
DE POI, Pietro
core   +1 more source

Discovery and characterization of submarine groundwater discharge in the Siberian Arctic seas: a case study in the Buor-Khaya Gulf, Laptev Sea [PDF]

The Cryosphere, 2017
It has been suggested that increasing terrestrial water discharge to the Arctic Ocean may partly occur as submarine groundwater discharge (SGD), yet there are no direct observations of this phenomenon in the Arctic shelf seas.
A. N. Charkin, A. N. Charkin, M. Rutgers van der Loeff, N. E. Shakhova, N. E. Shakhova, Ö. Gustafsson, O. V. Dudarev, O. V. Dudarev, M. S. Cherepnev, A. N. Salyuk, A. V. Koshurnikov, E. A. Spivak, A. Y. Gunar, A. S. Ruban, I. P. Semiletov, I. P. Semiletov, I. P. Semiletov   +16 more
doaj   +1 more source

Variability of anti-Müllerian hormone and folliculotropic hormone levels in women of reproductive age in relation to normal or impaired ovarian function

Anthropological Review
The demographic crisis in Europe is growing due to an increasing proportion of couples with fertility disorders. The purpose of this study was to examine the variability of ovarian reserve markers with age in women with premature ovarian insufficiency ...
Małgorzata Jusiakowska-Piputa, Maria Kaczmarek   +1 more
doaj   +1 more source

Association between premature ovarian insufficiency and gut microbiota

BMC Pregnancy and Childbirth, 2021
Background Premature ovarian insufficiency (POI) is characterized by impairment of ovarian function on a continuum before the age of 40 years. POI is affected by multiple factors.
Jiaman Wu, Yuanyuan Zhuo, Yulei Liu, Yan Chen, Yan Ning, Jilong Yao   +5 more
doaj   +1 more source

PSYNDEX Tests Review für POI - SHOSTROM'S PERSONAL ORIENTATION INVENTORY

, 1988
This is a PSYNDEX Tests Review of POI - SHOSTROM'S PERSONAL ORIENTATION INVENTORY. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Kroiss, Josef
core   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Environmental toxicant induced epigenetic transgenerational inheritance of ovarian pathology and granulosa cell epigenome and transcriptome alterations: ancestral origins of polycystic ovarian syndrome and primary ovarian insufficiency

Epigenetics, 2018
Two of the most prevalent ovarian diseases affecting women’s fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome (PCOS). Previous studies have shown that exposure to a number of environmental toxicants can promote
Eric Nilsson, Rachel Klukovich, Ingrid Sadler-Riggleman, Daniel Beck, Yeming Xie, Wei Yan, Michael K. Skinner   +6 more
doaj   +1 more source

Senno del poi o senno di poi?

Italiano digitale, 2021
In questi ultimi tempi diverse persone attente e sensibili ai fatti di lingua si sono rivolte al servizio di Consulenza linguistica dell’Accademia della Crusca per sapere se sia corretto dire col senno del poi, o non piuttosto col senno di poi.
openaire   +3 more sources