Results 81 to 90 of about 506,179 (291)

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

Human umbilical cord mesenchymal stem cells restore the ovarian metabolome and rescue premature ovarian insufficiency in mice

open access: yesStem Cell Research & Therapy, 2020
Background Premature ovarian insufficiency (POI) is an ovarian dysfunction that seriously affects a woman’s physiological health and reproduction. Mesenchymal stem cell (MSC) transplantation offers a promising treatment option for ovarian restoration in ...
Yan Zhao   +11 more
doaj   +1 more source

On Congruences of Linear Spaces of Order One [PDF]

open access: yes, 2007
After presenting the main notions and results about congruences of k-planes, we dwell upon congruences of lines, mainly of order one. We survey the classification results in the projective spaces of dimension 3 and 4, which are almost complete, and ...
De Poi, Pietro, Mezzetti, Emilia
core   +1 more source

Therapeutic Potential of Fecal Microbiota Transplantation for Male Sexual Dysfunction: Evidence and Clinical Perspectives

open access: yesMicrobiota Medicine Research, EarlyView.
ABSTRACT Fecal microbiota transplantation (FMT), a microbiome‐based therapy, shows potential in treating male sexual dysfunction. Research into the influence of FMT on male sexual function has recently garnered increasing attention. This review aims to explore the impact of FMT on male sexual function and the underlying mechanisms, and to analyze the ...
Junyi Chen   +4 more
wiley   +1 more source

Design and Synthesis of Polyamine‐Proteolysis Targeting Chimera Conjugates for Histone Deacetylase (HDAC) Degradation with Enhanced Cellular Uptake

open access: yesChemistryOpen, EarlyView.
In this article, proteolysis targeting chimeras (PROTACs) bearing a polyamine linker capable of crossing cancer cell membranes via the polyamine transport system are synthesized and evaluated. The results provide valuable insights for the design of PROTACs with enhanced cellular uptake efficiency.
Yanran Liu   +6 more
wiley   +1 more source

Count Bayesian models for genetic analysis of in vitro embryo production traits in Guzerá cattle

open access: yesAnimal, 2017
Four models for in vitro embryo production traits in Guzerá cattle were compared: Gaussian (untransformed variable – LIN and transformed in logarithmic scale – LOG), Poisson (POI) and zero-inflated Poisson (ZIP).
B.C. Perez   +5 more
doaj   +1 more source

Sustainable Development of the Flemish Greenhouse Industry [PDF]

open access: yes
This paper addresses the sustainable development of the Flemish greenhouse industry by investigating the optimal size, structure and location of its farms. It emphasizes the importance of a square shape of the greenhouse as optimal structure.
Mathijs, Erik, Verwilt, Poi
core   +1 more source

On Strengthening the Logic of Iterated Belief Revision: Proper Ordinal Interval Operators [PDF]

open access: yes, 2018
Darwiche and Pearl’s seminal 1997 article outlined a number of baseline principles for a logic of iterated belief revision. These principles, the DP postulates, have been supplemented in a number of alternative ways.
Booth, Richard, Chandler, Jake
core   +1 more source

A Survey of Location Prediction on Twitter

open access: yes, 2018
Locations, e.g., countries, states, cities, and point-of-interests, are central to news, emergency events, and people's daily lives. Automatic identification of locations associated with or mentioned in documents has been explored for decades.
Han, Jialong, Sun, Aixin, Zheng, Xin
core   +1 more source

AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley   +1 more source

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