Results 91 to 100 of about 147,233 (294)

MAGIICAT V. Orientation of Outflows and Accretion Determine the Kinematics and Column Densities of the Circumgalactic Medium

open access: yes, 2015
We investigate the dependence of gas kinematics and column densities in the MgII-absorbing circumgalactic medium on galaxy color, azimuthal angle, and inclination to trace baryon cycle processes.
Churchill, Christopher W.   +4 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A Shape Optimization Method of a Specified Point Absorber Wave Energy Converter for the South China Sea

open access: yesEnergies, 2018
In this paper, a shape optimization method of a truncated conical point absorber wave energy converter is proposed. This method converts the wave energy absorption efficiency into the matching problem between the wave spectrum of the South China Sea and ...
Yadong Wen   +6 more
doaj   +1 more source

More absorbers in hyperspaces

open access: yes, 2016
The family of all subcontinua that separate a compact connected $n$-manifold $X$ (with or without boundary), $n\ge 3$, is an $F_\sigma$-absorber in the hyperspace $C(X)$ of nonempty subcontinua of $X$.
Krupski, Paweł, Samulewicz, Alicja
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Analysis on Energy Harvesting Mechanism of Compartmented Buoy Wave Energy Converter

open access: yes南方能源建设
[Objective] The motion attitude of oscillating buoy wave energy converters significantly impacts energy capture, and the compartmentalization characteristics of the buoy are closely related to its motion attitude. Therefore, it has significant importance
Yang LIU   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A New Solution for Sea Wave Energy Harvesting, the Proposal of an Ironless Linear Generator

open access: yesJournal of Marine Science and Engineering, 2020
The paper investigates an innovative ironless linear generator, installable inside a wave energy converter, in order to produce electricity from sea waves.
Domenico Curto   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Wave-to-Wire Power Maximization Control for All-Electric Wave Energy Converters with Non-Ideal Power Take-Off

open access: yesEnergies, 2019
The research presented in this paper investigates novel ways of optimizing all-electric wave energy converters for maximum wave-to-wire efficiency. In addition, a novel velocity-based controller is presented which was designed specifically for wave-to ...
Marios Charilaos Sousounis   +1 more
doaj   +1 more source

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