Results 71 to 80 of about 1,830,967 (336)

GPV-Pose: Category-level Object Pose Estimation via Geometry-guided Point-wise Voting [PDF]

, 2022
Di Yan, Ruida Zhang, Zhiqiang Lou, Fabian Manhardt, Xiangyang Ji, Nassir Navab, Federico Tombari   +6 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Holographic two-point functions in a disorder system

Physics Letters B, 2023
We study the holographic dual of two-point correlation functions for nonconformal field theories. We first take into account a Lifshitz geometry as the dual of a Lifshitz field theory which may appear at a critical or IR fixed point.
Chanyong Park
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Accurate deformation analysis based on point position uncertainty estimation and adaptive projection point cloud comparison

Geocarto International, 2023
The accuracy of the scanning scene representation and corresponding points extraction are key factors in deformation analysis based on point cloud. Still, little is known about the influence of terrestrial laser scanner (TLS) survey properties on point ...
Wenxiao Sun, Jian Wang, Yikun Yang, Fengxiang Jin, Fuxun Sun   +4 more
doaj   +1 more source

Deconvolution\nof Phonon Scattering by Ferroelectric\nDomain Walls and Point Defects in a PbTiO₃ Thin Film Deposited\nin a Composition-Spread Geometry [PDF]

, 2021
David Bugallo, Eric Langenberg, Elías Ferreiro‐Vila, Eva H. Smith, Christina Stefani, X. Batlle, Gustau Catalán, Neus Domingo, Darrell G. Schlom, F. Rivadulla   +9 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Advanced Patch-Based Affine Motion Estimation for Dynamic Point Cloud Geometry Compression

Sensors
The substantial data volume within dynamic point clouds representing three-dimensional moving entities necessitates advancements in compression techniques. Motion estimation (ME) is crucial for reducing point cloud temporal redundancy.
Yiting Shao, Wei Gao, Shan Liu, Ge Li
doaj   +1 more source

BIM RECONSTRUCTION: AUTOMATED PROCEDURAL MODELING FROM POINT CLOUD DATA [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
The reconstruction of Building Information Modeling objects for as-built modeling is currently the subject of ongoing research. A popular method is to extract structure information from point cloud data to create a set of parametric objects.
M. Bassier, L. Mattheuwsen, M. Vergauwen
doaj   +1 more source