Results 71 to 80 of about 7,665,845 (335)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
ON PRECISION ACOUSTIC WAVE CALCULATION IN A FREQUENCY DOMAIN
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2022 The accuracy of the calculation of acoustic problems formulated in the frequency domain is presented in this work. The issues of the acoustic point sources modelling were discussed and the influence of frequency as well as the impact of the geometry of ...
Tomasz Rymarczyk, Jan Sikora
doaj +1 more source
Automatic normal orientation in point clouds of building interiors
, 2019 Orienting surface normals correctly and consistently is a fundamental problem in geometry processing. Applications such as visualization, feature detection, and geometry reconstruction often rely on the availability of correctly oriented normals.
J Wang +5 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Holographic two-point functions in a disorder system
Physics Letters B, 2023 We study the holographic dual of two-point correlation functions for nonconformal field theories. We first take into account a Lifshitz geometry as the dual of a Lifshitz field theory which may appear at a critical or IR fixed point.
Chanyong Park
doaj +1 more source
Point-wise Symmetry of Birkhoff-James Orthogonality and Geometry of $\mathbb{B}(\ell_\infty^n,\ell_1^m)$ [PDF]
, 2022 Babhrubahan Bose
openalex +1 more source
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Geocarto International, 2023 The accuracy of the scanning scene representation and corresponding points extraction are key factors in deformation analysis based on point cloud. Still, little is known about the influence of terrestrial laser scanner (TLS) survey properties on point ...
Wenxiao Sun +4 more
doaj +1 more source
A Texture Integrated Deep Neural Network for Semantic Segmentation of Urban Meshes
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2023 3-D geo-information is essential for many urban related applications. Point cloud and mesh are two common representations of the 3-D urban surface. Compared to point cloud data, mesh possesses indispensable advantages, such as high-resolution image ...
Yetao Yang +3 more
doaj +1 more source