Results 91 to 100 of about 836,803 (300)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Técnicas de inyección de fallos basadas en FPGAs para la evaluación de la tolerancia a fallos de tipo SEU en circuitos digitales [PDF]

open access: yes, 2007
Este trabajo de tesis doctoral presenta nuevas técnicas de inyección de fallos transitorios en elementos de memoria, que permiten la evaluación del comportamiento de los complejos circuitos digitales actuales en presencia de fallos SEU (Single Event ...
Portela García, Marta
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Interfacial instabilities: implications for multi-material moulding [PDF]

open access: yes
This work investigates and identifies the mechanisms that are at work in the creation of instabilities during co-injection moulding. Two aspects are investigated, neither of which has been previously reported.
Goodship, Vannessa
core  

Device for Checking Acuteness of Injection Needle Point and Test Methodology

open access: yesНаука и техника, 2019
The paper presents a designed device for checking acuteness of injection needle point and development of methodology for conducting corresponding tests.
M. G. Kiselev   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Experimental aeroacoustics study on jet noise reduction using tangential air injection

open access: yes, 2011
PhDAircraft jet exhausts are a source of undesirable noise and continue to be an area of investigation driven by increasingly stringent regulation. The noise is produced by the unsteady mixing of the jet with the surrounding air and is dominated by the ...
Ahmad, Arsalan
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Evaluation of Novel Imidazotetrazine Analogues Designed to Overcome Temozolomide Resistance and Glioblastoma Regrowth

open access: yes, 2014
The cellular responses to two new temozolomide (TMZ) analogues, DP68 and DP86, acting against glioblastoma multi- forme (GBM) cell lines and primary culture models are reported.
Wheelhouse, Richard T.   +15 more
core   +1 more source

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