Results 81 to 90 of about 6,150,813 (282)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Evaluation of methylene blue solution distribution in the four-point transversus abdominis plane block technique in pigs: a pilot anatomical study

open access: yesFrontiers in Veterinary Science
AimThis prospective pilot anatomical study aimed to develop an ultrasound-guided transversus abdominis plane (TAP) block technique that desensitises cranial and mid-abdominal wall in grower pigs.
Jerneja Sredenšek   +8 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

EXFI: a low cost Fault Injection System for embedded Microprocessor-based Boards [PDF]

open access: yes, 1998
Evaluating the faulty behavior of low-cost embedded microprocessor-based boards is an increasingly important issue, due to their adoption in many safety critical systems. The architecture of a complete Fault Injection environment is proposed, integrating
SONZA REORDA, Matteo   +8 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Myositis ossificans of the elbow after a trigger point injection.

open access: yes, 2021
Trigger point injection is a simple procedure that is widely performed for relieving pain. Even though there are several complications of trigger point injection, myositis ossificans has not been documented as one of its complications.
신상진
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Pavee Point strategic plan 2006-2010

open access: yes, 2006
Pavee Point ...
Pavee Point Travellers Centre
core  

Clinical Study on Applying the Combination of Psychological Therapy and Point Injection in Childbirth Analgesia

open access: yesHuli yanjiu, 2003
Objective: to probe into the impacts of applying the combination of psychological therapy and point injection on childbirth analgesic effect and on mothers and infants.
孔令君
doaj  

Home - About - Disclaimer - Privacy