Results 61 to 70 of about 836,803 (300)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Myositis ossificans of the elbow after a trigger point injection.

, 2021
Trigger point injection is a simple procedure that is widely performed for relieving pain. Even though there are several complications of trigger point injection, myositis ossificans has not been documented as one of its complications.
신상진
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Study of Injection Moulding with Bismuth Alloy

, 2013
There is a demand to produce parts in small quantities, using cost effective injection moulding processes. The emerging economic case suggests there will be advantages in producing injection moulding tools for short duration low volume production runs ...
Unver, Ertu, Durgun, Ismail, Jagger, Brian, Kus, Abdil, University of Uludag, University of Huddersfield, Tofas   +6 more
core  

Experimental study on effect of N2 on physical parameters and phase equilibrium patterns of CO2-rich injection gas [PDF]

Youqicang pingjia yu kaifa
The high cost of industrial flue gas treatment makes injecting CO₂-rich exhaust gas into depleted oil and gas reservoirs a potential technology for enhanced recovery and carbon sequestration. This study aims to guide the injection process, and the effect
QIN Nan, GAN Xiaofei, LUO Yu, LIU Xiaoxu, WEN Bin, CHEN Xingyu
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

FPGA-based fault injection design for 16K-point FFT processor

The Journal of Engineering, 2019
There are a number of satellites working in the harsh space environment. The charged particles in space may strike the electron devices causing the undesired influences, such as soft errors in memory devices or permanent damage in hardware circuits ...
Chuang-An Mao, Yu Xie, Xin Wei, Yi-Zhuang Xie, He Chen   +4 more
doaj   +1 more source

Characterization of shrinkage effects in micro-injection moulding (µ-IM) [PDF]

, 2013
This thesis characterizes the effects on shrinkage in microinjection moulding. The literature review considers four branches of investigation (material properties, processing parameters, mould design and specimen design).
Annicchiarico, Daniele
core  

A New Characterization Method for Dynamic Connectivity Field Between Injection and Production Wells in Offshore Reservoir

Journal of Marine Science and Engineering
Connectivity between injection and production wells is critical for efficient oil production, especially in offshore reservoirs where the number of wells is limited.
Changchun Guo, Yuzhou Hu, Li Tao, Mengna Cheng, Fankun Meng, Hui Zhao, Fengshuang Du   +6 more
doaj   +1 more source