Results 41 to 50 of about 6,150,813 (282)

The function of point injection in improving learning and memory dysfunction caused by cerebral ischemia

open access: yesJournal of Pharmacopuncture, 2001
This experiment has investigated the influence of Yamen (Du. 15) point injection on learning and memory dysfunction caused by cerebral ischemia and reprofusion in bilateral cervical general artery combined with bleeding on mouse tail to mimic vascular ...
Chen Hua-De
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Preliminary Study on Point-injection

open access: yesHuli yanjiu, 1994
谈穴位注射250011山东中医学院附属医院刘华关键词穴位,注射PreliminaryStudyonPoint-injection¥LiuHua(AffiliatedHospital,ShandongChineseTraditionalMedicalC...
刘华
doaj  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Treatment of Chronic Enteritis with Point Injection

open access: yesHuli yanjiu, 1995
慢性肠炎是临床上较常见的疾病,此病很顽固,长年腹泻,经久不愈,患者非常痛苦,面黄肌瘦,疲乏无力,用药物治疗效果不佳。我科近年来用维生素B12足三里穴位注射治疗慢性肠炎,收到满意的效果。现介绍如下。 1 方法 1.1 取穴外膝眼直下3寸,距胫骨前嵴一横指处即为足三里穴。 1.2 操作方法患者取坐位或卧位,常规消毒针刺部位的皮肤 ...
秦新华, 丁伟
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Fault Injection for Embedded Microprocessor-based Systems [PDF]

open access: yes, 1999
Microprocessor-based embedded systems are increasingly used to control safety-critical systems (e.g., air and railway traffic control, nuclear plant control, aircraft and car control).
Rebaudengo,Maurizio   +6 more
core   +1 more source

Study on the Treatment of Urine Retention with Acu - point Injection after Rectocolonic Operation

open access: yesHuli yanjiu, 1996
肛肠术后患者常出现尿潴留。笔者自1991年~1994年运用中医传统疗法即穴位注射法,对80例肛肠术后尿潴留患者行两侧足三里穴注射甲基硫酸新斯的明注射液,取得良好效果,现报告如下。
李连岁
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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