Results 121 to 130 of about 12,112,488 (299)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Erratum to: Geotechnical and mineralogical properties of weak rocks from Central Greece
Open Geosciences, 2012 Ilia Ioanna +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Load Cell Test Pada Fondasi Jembatan Suramadu [PDF]
, 2008 At present, Suramadu Bridge is the longest bridge in Indonesia, having 5.438 m length. The uniqueness of this bridge is the three parts which divide the bridge, those are approaching bridge, main bridge, and causeway.
Made, Suangga
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Tractor Testing; Load Units; Centaur
, 1948 "Using Centaur as loading unit following test no. 402." Side view of the Centaur KV-48 tractor on the test track. Not clear why the front is lifted, but it might have been because the steering system didn't allow the Centaur to be towed since it didn't ...
Nebraska Tractor Test Laboratory
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Stress and Coping Inventory (2nd, revised and standardized edition)
Die Revision des Stress- und Coping-Inventars (SCI) erfasst mit insgesamt sieben Skalen und 45 Items psychische Stressbelastung, Stresssymptome und Stressbewältigungsstrategien.
Satow, L.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Point-of-care viral load testing and differentiated HIV care [PDF]
The Lancet HIV, 2018 Dorward, J, Drain, P, Garrett, N
openaire +2 more sources