Results 51 to 60 of about 432,044 (264)

A proposal of an inverse analysis method for estimating nonlinear stress-strain relation from three-point bending test

Nihon Kikai Gakkai ronbunshu, 2015
An inverse analysis method was proposed for estimating nonlinear stress-strain curve with plastic deformation from load-deflection curve of three-point bending test of simply supported beam with rectangular cross section. This method was based on a small
Yuko SAWADA, Shiro KUBO
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Strain-stress experimental behaviour of tapered columns in single-span frames/Trapecinių kolonų vienanaviuose rėmuose deformacijų-įtempių būvis

Journal of Civil Engineering and Management, 2000
Two single-span frame tests were carried out. The width of frame is 6m, column's height 4.17m. Frame supports are pinned. Connection between column and beam is rigid. Beam of the frame was loaded with two vertical and one horizontal loads.
Vaidotas Šapalas
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Development of empirical equations between uniaxial compressive strength and point load index: a case study for sandy dolomite

Scientific Reports
In this research, the Yuxi section of Central Yunnan Water Diversion Project in Southwest of China, including the tunnel and the traversed sandy dolomite along its route, was selected as the research area, and different sandification degrees ...
Meiqian Wang, Wenlian Liu, Haiming Liu, Wei Xu   +3 more
doaj   +1 more source

Experiment and Calibration of Finite Element Parameters of Pineapple Based on Cohesive Zone Model

Agriculture
In view of the lack of research on the extrusion of pineapple caused by the overall stress response of pineapple at the present stage of pineapple automatic harvesting, the finite element model of pineapples can be studied by constructing such a model ...
Dexuan Pan, Fengguang He, Qin Zhang, Ganran Deng, Guojie Li, Zhende Cui, Pinlan Chen, Jiehao Li   +7 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Estimation of Uniaxial Compressive Strength and Tensile Strength of Sandstone Based on Point Load

Renmin Zhujiang
In rock mechanics and engineering practice, accurate and rapid evaluation of uniaxial compressive strength and tensile strength of rock is important for engineering design and construction safety. Traditional test methods are time-consuming and laborious,
LIU Yongzhi, FANG Qingyao, ZHANG Kun, YAO Huayan, LIU Wu, LIU Guang   +5 more
doaj   +2 more sources