Results 121 to 130 of about 7,351,528 (349)
Point mutation of the mitochondrial tRNA(Leu) gene (A 3243 G) in maternally inherited hypertrophic cardiomyopathy, diabetes mellitus, renal failure, and sensorineural deafness. [PDF]
, 1995 Sylvie Manouvrier +9 more
openalex +1 more source
A Point Mutation in Sec61α1 Leads to Diabetes and Hepatosteatosis in Mice
Diabetes, 2009 OBJECTIVE Type 2 diabetes is caused by both environmental and genetic factors. To better understand the genetic factors we used forward genetics to discover genes that have not previously been implicated in the development of hyperglycemia or diabetes ...
David J. Lloyd +2 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Application of a periodic table for the genetic code to influenza A/H3N2 virus [PDF]
, 2007 If biologists can utilize a table to have access to biological phenomena in the manner analogous to the periodic table for chemical elements, they may get hold of a directing post in life science.
Susumu Morimoto
core +1 more source
Diverse point mutations result in glucose-6-phosphate dehydrogenase (G6PD) polymorphism in Taiwan [PDF]
, 1992 Tang K. Tang +5 more
openalex +1 more source
PLoS Neglected Tropical Diseases, 2009 Background Resistance of Aedes aegypti to photostable pyrethroid insecticides is a major problem for disease-vector control programs. Pyrethroids target the voltage-gated sodium channel on the insects' neurons.
H. Kawada +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The allelic partition for coalescent point processes [PDF]
, 2009 Assume that individuals alive at time $t$ in some population can be ranked in such a way that the coalescence times between consecutive individuals are i.i.d. The ranked sequence of these branches is called a coalescent point process.
Lambert, Amaury
core +2 more sources
A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation. [PDF]
, 1987 Joseph Couto +3 more
openalex +1 more source