Results 191 to 200 of about 6,585,062 (339)

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Fluoroquinolone-resistant Salmonella Paratyphi A

Emerging Infectious Diseases, 2005
Takuya Adachi, Hiroko Sagara, Kenji Hirose, Haruo Watanabe   +3 more
doaj   +1 more source

A point mutation in the photosystem II protein PsbW disrupts thylakoid organization and alters starch granule formation. [PDF]

Plant Physiol
Ilse TE, Zhang H, Heutinck A, Liu C, Eicke S, Sharma M, Pfister B, Santelia D, Zeeman SC.   +8 more
europepmc   +1 more source

Point mutations of rhodopsin gene found in Japanese families with autosomal dominant retinitis pigmentosa (ADRP) [PDF]

, 1992
Keiko Fujiki, Yoshihiro Hotta, Mutsuko Hayakawa, Hitoshi Sakuma, Takeshi Shiono, Michiru Noro, Takehiko Sakuma, Makoto Tamai, Kazumasa Hikiji, Ryuji Kawaguchi, Akihiko Hoshi, Akira Nakajima, Atsushi Kanai   +12 more
openalex   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Amino acid substitutions in succinate dehydrogenase complex conferring resistance to the SDHI fungicide pydiflumetofen in Cochliobolus heterostrophus causing southern corn leaf blight

Journal of Integrative Agriculture
Southern corn leaf blight (SCLB) caused by Cochliobolus heterostrophus, is a widespread foliar disease that has a substantial impact on maize yield in the Huang-Huai-Hai Region of China. Pydiflumetofen (Pyd), a new succinate dehydrogenase inhibitor (SDHI)
Jiazhi Sun, Bingyun Yang, Lingmin Xia, Rui Yang, Chaoyang Ding, Yang Sun, Xing Chen, Chunyan Gu, Xue Yang, Yu Chen   +9 more
doaj  

Repeated clear benefits of immunotherapy in a patient with Charcot-Marie-Tooth disease carrying a rare point mutation in PMP22. [PDF]

Neurogenetics
Kawai H, Nishida Y, Kanda T, Yokota T.
europepmc   +1 more source

A comprehensive collection of point mutations in the internal promoter of the adenoviral VAI gene.

, 1987
Richard M. Rohan, Gary Ketner
openalex   +1 more source

Isolation and characterization of point mutations in the Escherichia coli grpE heat shock gene [PDF]

, 1994
Bin Wu, D. D. Ang, Mark Snavely, Costa Georgopoulos   +3 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source