Results 121 to 130 of about 3,602,130 (312)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Modeling of Cellular Networks Using Stationary and Nonstationary Point Processes

open access: yesIEEE Access, 2018
The spatial topology of the base stations in wireless networks has a profound impact on their performance evaluation and analysis. It is important to identify a proper and accurate point process model before applying any theoretical stochastic geometry ...
Chunlin Chen   +3 more
doaj   +1 more source

Point-process modeling of secondary crashes. [PDF]

open access: yesPLoS One, 2023
Motagi S   +4 more
europepmc   +1 more source

A gradient field approach to modelling fibre-generated spatial point processes [PDF]

open access: yes, 2011
A new non-parametric model is introduced for point processes that are clustered along curves or fibres, with additional background noise. The model identifies random curves as integral lines of a gradient field.
Thönnes, Elke   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Spatial Point Process for Estimating the Probability of Occurrence of a Traffic Accident. [PDF]

open access: yes
In this paper a pioneer method for evaluating the probability of occurrence of a traffic accident in different segments of national road is described.
Anastassios Karaganis, Angelos Mimis
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Bond markets where prices are driven by a general marked point process [PDF]

open access: yes
We investigate the term structure for the case when interest rates are allowed to be driven by a general marked point process as well as by a Wiener process.
Runggaldier, W., Kabanov, Y., Björk, T.
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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