Results 131 to 140 of about 3,276,976 (263)

Causal Discovery in High-Dimensional Point Process Networks with Hidden Nodes. [PDF]

Entropy (Basel), 2021
Wang X, Shojaie A.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Sleep slow oscillation emergence on the scalp as a renewal point process. [PDF]

PLoS Comput Biol
Alipour M, Mednick SC, Malerba P.
europepmc   +1 more source

Measuring the Rate of Information Exchange in Point-Process Data With Application to Cardiovascular Variability. [PDF]

Front Netw Physiol, 2021
Mijatovic G, Pernice R, Perinelli A, Antonacci Y, Busacca A, Javorka M, Ricci L, Faes L.   +7 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Age-Dependent Geographic Convergence of Overdose and Cardiovascular Emergency Medical Services Calls: A Spatial Point Process Analysis. [PDF]

Prev Chronic Dis
Pesarsick J, Bhandari R, Richards E, Groth C, Findley S, Hendricks B.   +5 more
europepmc   +1 more source

Point process models for COVID-19 cases and deaths. [PDF]

J Appl Stat, 2023
Gajardo Á, Müller HG.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Temporal point process modeling of aggressive behavior onset in psychiatric inpatient youths with autism. [PDF]

Sci Rep
Potter M, Everett M, Singh A, Stratis G, Watanabe Y, Demirkaya A, Erdogmus D, Imbiriba T, Goodwin MS.   +8 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source