Results 171 to 180 of about 10,528,015 (255)

Central Point Notice of Adopted Amendment (2008-05-19)

, 2008
14 pp. Adopted 2008-05-19. Department of Land Conservation and Development Notice of Adopted AmendmentThe attached approved amendment is the updated population and demographic element of the City of Central Point Comprehensive Plan.
Central Point (Or.)
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Double-helix optical point spread function enables real-time mesoscopic 3D functional microangiography in the living mouse brain and skull. [PDF]

Nat Commun
Zhang B, Guo S, Tang L, Chen Y, Glandorf L, Jessen E, Chang X, Jin T, Reiss M, Lyu S, Fu Q, Amata H, Heidrich W, Glück C, Schillinger D, Weber B, Deán-Ben XL, Wang W, Dun X, Razansky D, Chen Z, Zhou Q.   +21 more
europepmc   +1 more source

Optimized OCT-based depth-resolved model for attenuation compensation using point-spread-function calibration. [PDF]

Proc SPIE Int Soc Opt Eng, 2021
Wang Y, Wei S, Guo S, Kang JU.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Characterization of point-spread function specification error on Geometric Transfer Matrix partial volume correction in [¹¹C]PiB amyloid imaging. [PDF]

EJNMMI Phys, 2021
Laymon CM, Minhas DS, Royse SK, Aizenstein HJ, Cohen AD, Tudorascu DL, Klunk WE.   +6 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Enhanced supercritical angle localization microscopy through point spread function modeling. [PDF]

Biomed Opt Express
Khan SA, Lidke KA, Liu S.
europepmc   +1 more source

Effect of Point Spread Function Deconvolution in Reconstruction of Brain ¹⁸F-FDG PET Images on the Diagnostic Thinking Efficacy in Alzheimer's Disease. [PDF]

Front Med (Lausanne), 2021
Doyen M, Mairal E, Bordonne M, Zaragori T, Roch V, Imbert L, Verger A.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source