Results 61 to 70 of about 4,674,421 (280)
Generalized point vortex dynamics on $CP ^2$
Journal of Geometric Mechanics, 2018 This is the second of two companion papers. We describe a generalization of the point vortex system on surfaces to a Hamiltonian dynamical system consisting of two or three points on complex projective space CP^2 interacting via a Hamiltonian function depending only on the distance between the points. The system has symmetry group SU(3).
Montaldi, James, Shaddad, Amna
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
The motion of a singular vortex near an escarpment [PDF]
, 2001 McDonald (1998) has studied the motion of an intense, quasi-geostrophic, equivalent barotropic, singular vortex near an infinitely long escarpment. The present work considers the remaining cases of the motion of weak and moderate intensity singular ...
Johnson, ER, Dunn, DC, McDonald, NR
core
Interactions of point vortices in the Zabusky-McWilliams model with a background flow [PDF]
, 2012 We combine a simple quasi-geostrophic flow model with the Zabusky-McWilliams theory of atmospheric vortex dynamics to address a hurricane-tracking problem of interest to the insurance industry.
Connaughton, Colm, Ockendon, J. R.
core +1 more source
Dynamics of vortex shedding from slender cones [PDF]
, 2009 PhDThe dynamics of vortex shedding from bluff bodies has been investigated experimentally for many decades, with the simple geometric case for the investigation being a uniform circular cylinder aligned with its axis normal to the flow. Even though
Jagadeesh, Chetan Sakaleshpur
core +3 more sources
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Vortex equilibria in flow past a plate [PDF]
, 2008 Families of vortex equilibria, with constant vorticity, in steady flow past a flat plate are computed numerically. An equilibrium configuration, which can be thought of as a desingularized point vortex, involves a single symmetric vortex patch located ...
McDonald, NR
core
Research on the Vortex States of Partially Coherent Vortex Beams
PhotonicsThe Mutual Optical Intensity (MOI) model is further developed to simulate the propagation of partially coherent X-ray vortex beams through free space. The intensity, phase, and amplitude distributions of the degree of coherence in the far field zone are ...
Weihong Sun +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source