Results 91 to 100 of about 492,052 (313)
Influence of Restrictions on Range of View From Cockpit in Operation of Hydraulic Excavator
We investigated the effect of restricting the field of view from the cockpit on the operation of a hydraulic excavator. We developed a computer simulation for the turning operation of an excavator and we performed an experiment.
Kazuyuki Matsumura +4 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
RF-Assisted Uncertainty Cone Reduction in Free-Space Optical Inter-Satellite Links
One of the space communications industry’s current focuses is developing high-throughput communication terminals for satellite-to-satellite communication links.
Elena Fernandez-Nino +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The ManyDogs 1 study is the first multi-site collaborative study of dogs’ responses to human pointing. It addressed whether dogs perceive the gesture as socially communicative and are therefore more likely to follow the point when it is paired with ...
ManyDogs Project +5 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Head–torso–hand coordination in children with and without developmental coordination disorder
AIM: This study investigated the nature of coordination and control problems in children with developmental coordination disorder (DCD). METHOD: Seven adults (two males, five females, age range 20–28y; mean 23y, SD 2y 8mo) and eight children with DCD (
Sheehan, Sinead +17 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A major challenge in robotics and computational neuroscience is relative to the posture/movement problem in presence of kinematic redundancy. We recently addressed this issue using a principled approach which, in conjunction with nonlinear inverse ...
Paolo Tommasino, Domenico Campolo
doaj +1 more source

