Results 81 to 90 of about 492,052 (313)

The VLT/ERIS vortex coronagraph: design, pointing control, and on-sky performance [PDF]

editorial reviewedThe Enhanced Resolution Imager and Spectrograph (ERIS) is the new near-infrared instrument at the VLT-UT4. ERIS replaces and extends the observational capabilities formerly provided by SINFONI and NACO: integral field spectroscopy at 1 -
Quanz, Sascha P., Huby, E., Grani, Paolo, Puglisi, Alfio, Grani, P., Bonse, Markus, Zins, Gérard, Glauser, Adrian M., Kenworthy, Matt, Dannert, F., Baruffolo, A., Absil, O., Hayoz, J., Glauser, A.M., Salasnich, Bernardo, Huby, Elsa, Puglisi, A., Bonse, M.J., Dannert, Felix, Davies, R., Quanz, S.P., Absil, Olivier, Baruffolo, Andrea, De Rosa, R.J., Kenworthy, M.A., Orban De Xivry, Gilles, Davies, Ric, Taylor, William, Hayoz, Jean, Salasnich, B., Taylor, W., De Rosa, Robert, Orban de Xivry, G., Zins, G.   +33 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

How do we know what we are doing? Time, intention and awareness of action

, 2008
Time is a fundamental dimension of consciousness. Many studies of the "sense of agency" have investigated whether we attribute actions to ourselves based on a conscious experience of intention occurring prior to action, or based on a reconstruction after
Sarrazin, Jean-Christophe, Cleeremans, A, Haggard, P, Cleeremans, Axel, Sarrazin, JC, Haggard, P.   +5 more
core   +1 more source

The origin of pointing

, 2022
Pointing gestures play a foundational role in human language, but up to now, we have not known where these gestures come from. Here, we investigated the hypothesis that pointing originates in touch.
Strickland, Brent, Kachel, Gregor, O'Madagain, Cathal   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Low Rates of Pointing in 18-Month-Olds at Risk for Autism Spectrum Disorder and Extremely Preterm Infants: A Common Index of Language Delay?

Frontiers in Psychology, 2019
Infants with an older sibling with an Autism Spectrum Disorder diagnosis (Sibs ASD) are at high risk for language delay (LD) as well as infants born preterm, especially those with an extremely low gestational age (ELGA, GA ≤ 28 weeks).
Alessandra Sansavini, Annalisa Guarini, Mariagrazia Zuccarini, Jessica Zong Lee, Giacomo Faldella, Jana Marie Iverson   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Nested task constraints shape continuous perception-action coupling control during human locomotor pointing

, 2004
Behavioural studies of human locomotor pointing have been dominated by specific task constraints of generating maximal approach velocity towards spatial targets.
Davids, Keith W., Renshaw, I, Davids, K, Renshaw, Ian   +3 more
core   +1 more source

Theory and system research of communication with tracking and pointing function for hunter robot

Tongxin xuebao, 2011
Eye-hole wave communication frame was proposed first time.Tracking and pointing model of communication was put forward.New era of short distance optical communication was pioneered.Acguisition method of beaconing light was researched and acquisition time
YU Yang1, MIN Fu-hong2, NI Xiao-wu1, ZHANG Hong-chao1   +3 more
doaj