Results 101 to 110 of about 571,071 (309)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Topology Optimization of the Bracket Structure in the Acquisition, Pointing, and Tracking System Considering Displacement and Key Point Stress Constraints

Aerospace
The lightweight and displacement-stable design of the mechanical support structure within the APTS (Acquisition, Pointing, and Tracking System) is crucial for enhancing the payload capacity of remote sensing, satellite communication, and laser systems ...
Bo Gao, Hongtao Yang, Weining Chen, Hao Wang   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Adaptive Pointing Design and Evaluation of a Precision Enhancing Technique for Absolute Pointing Devices

, 2009
We present Adaptive Pointing, a novel approach to addressing the common problem of accuracy when using absolute pointing devices for distant interaction.
Werner A. König, Jens Gerken, Gerken, Jens, Dierdorf, Stefan, Reiterer, Harald, König, Werner A., Harald Reiterer, Stefan Dierdorf   +7 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Pointing at you

, 1946
Fr. Maruca standing next to a pointing totem pole in Ketchikan.Fr.

core   +1 more source

Effect of text height and line spacing of link text on operability of portable terminal with touch screen

Nihon Kikai Gakkai ronbunshu, 2019
Recently, the use of portable terminals with touch screens such as smartphones has spread rapidly. Many users have used these devices to browse the internet or social networking services (SNS).
Taiga UJI, Takahiro NISHIMURA, Kouki DOI, Hiroshi FUJIMOTO   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gaze- vs. handbased pointing in virtual environments

, 2003
This paper contributes to the nascent body of literature on pointing performance in Virtual Environments (VEs), comparing gaze- and hand-based pointing.
Nathan Cournia, John D. Smith, Andrew T. Duchowski   +2 more
core   +1 more source