Results 61 to 70 of about 114,399 (242)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The online monitoring of pointing error (PE) caused by the main reflector (MR) deformation under wind disturbance has become a knotty problem for large reflector antennas.
Wei Liang, Jin Huang, Jie Zhang
doaj +1 more source
Amplitude and direction errors in kinesthetic pointing
We investigated the accuracy with which, in the absence of vision, one can reach again a 2D target location that had been previously identified by a guided movement. A robotic arm guided the participant's hand to a target (locating motion) and away from it (homing motion). Then, the participant pointed freely toward the remembered target position.
BAUD BOVY , GABRIEL, VIVIANI P.
openaire +4 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
With the continuous improvement of remote sensing satellite resolution, laser communication technology has gained significant traction. The pointing accuracy of ground-based laser communication terminals is critical for the stability of satellite–ground ...
Wenyan Li +6 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The eff ect of beam center shift on the performance of satellite chaos laser safety communication system in spaceintegrated-ground information network was studied, the bit error rate (BER) formulae with external and internal mismatch caused by beam ...
Mi LI +5 more
doaj +2 more sources
A Digital Twin Model for Optical Telescope Pointing Systems
Pointing accuracy, as one of the important indexes to measure the performance of optical tele-scope products, is directly related to the observation quality and efficiency of the telescope, but affected by a variety of complex factors, the timeliness ...
Zhenghao Li, Yahui Zhang, Yan He
doaj +1 more source

