Results 71 to 80 of about 78,267 (285)

Error budget analysis of SCIAMACHY limb ozone profile retrievals using the SCIATRAN model [PDF]

Atmospheric Measurement Techniques, 2013
A comprehensive error characterization of SCIAMACHY (Scanning Imaging Absorption Spectrometer for Atmospheric CHartographY) limb ozone profiles has been established based upon SCIATRAN transfer model simulations.
N. Rahpoe, C. von Savigny, M. Weber, A.V. Rozanov, H. Bovensmann, J. P. Burrows   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Performance comparison between uniformly and nonuniformly spaced adaptive antennas with respect to tolerance to pointing errors

, 2006
The paper presents theoretical and experimental investigations into performances of narrowband uniformly and nonuniformly spaced adaptive linear dipole array antennas that are subjected to pointing errors.
Homer, J. P., Bialkowski, M. E., Al-Ka'bi, A. H.   +2 more
core   +1 more source

Ergodic Capacity Analysis of Decode-and-Forward Relay-Assisted FSO Systems Over Alpha–Mu Fading Channels Considering Pointing Errors

IEEE Photonics Journal, 2016
The ergodic capacity of decode-and-forward (DF) relay-assisted free-space optical (FSO) communication systems when line of sight is available is analyzed over gamma–gamma fading channels with pointing errors.
Ruben Boluda-Ruiz, Antonio Garcia-Zambrana, Beatriz Castillo-Vazquez, Carmen Castillo-Vazquez   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A new calibration model for pointing a radio telescope that considers nonlinear errors in the azimuth axis

, 2014
A new calibration model of a radio telescope that includes pointing error is presented, which considers nonlinear errors in the azimuth axis. For a large radio telescope, in particular for a telescope with a turntable, it is difficult to correct pointing
Wang, Jin-Qing, Kong, De-Qing, Wang, Song-Gen, Wang, Min, Zhang, Hong-Bo   +4 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Improved beamforming for FSO MISO system over gamma-gamma fading with pointing errors

, 2016
International audienceIn this paper, we study the problem of feedback based beamforming for multiple-input single-output free space optical (FSO) system with pointing errors.
Bhatnagar, Manav R., Ankit Garg, Olivier Berder, Vrigneau, Baptiste, Manav R. Bhatnagar, Berder, Olivier, Garg, Ankit, Baptiste Vrigneau   +7 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source