Results 81 to 90 of about 78,267 (285)

The VLT/ERIS vortex coronagraph: design, pointing control, and on-sky performance [PDF]

open access: yes
editorial reviewedThe Enhanced Resolution Imager and Spectrograph (ERIS) is the new near-infrared instrument at the VLT-UT4. ERIS replaces and extends the observational capabilities formerly provided by SINFONI and NACO: integral field spectroscopy at 1 -
Quanz, Sascha P.   +33 more
core   +1 more source

A deep learning approach for predicting the antenna pointing error caused by transmission faults with simulation data

open access: yesScientific Reports
Reflector antenna has been widely used in deep space exploration, radar warning, and other fields, all of which requires high pointing accuracy. The antenna elevation bearings are the key component that guarantees its pointing accuracy, while any ...
Lihui Chen   +5 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Pointing Errors Reflect Biases in the Perception of the InitialHand Position

open access: yes, 1998
Vindras, Philippe, Michel Desmurget, Claude Prablanc, and Paolo Viviani. Pointing errors reflect biases in the perception of the initial hand position. J. Neurophysiol. 79: 3290–3294, 1998.
Michel Desmurget   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Estimation of Pointing Errors of Large Radio Telescopes under Solar Radiation Based on Digital Twin

open access: yes
The pointing accuracy of large radio telescopes is affected by antenna structure errors, installation errors, servo errors, gravity, and varying environmental factors.
Yongxiang Li   +7 more
core   +1 more source

Outage Probability of Mixed THz-UWOC Transmission Systems With Hardware Impairments

open access: yesIEEE Access
In this paper, we propose a mixed dual-hop communication system consisting of terahertz/underwater wireless optical communication (THz-UWOC) links with hardware impairments. In particular, considering the heterodyne detection, we assume that the THz link
Shenghai Chen, Lili Wan, Xianwu Mi
doaj   +1 more source

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