Results 81 to 90 of about 12,293 (303)

Open Informational Ecosystems: The Missing Link for Sharing Educational Resources

open access: yesInternational Review of Research in Open and Distributed Learning, 2015
Open educational resources are not available “as such”. Their provision relies on a technological infrastructure of related services that can be described as an informational ecosystem.
Michael Kerres , Richard Heinen
doaj  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Ethics of Truths and the Diasporic Novel: Radical Ethics in Ben Okri's The Famished Road

open access: yesCritical Literary Studies
This study queries into the ethical functions of diasporic fiction through carrying out a textual as well as a contextual study of The Famished Road. As an account of the politically marginal and the socially displaced, the diasporic novel is imbued with
Maryam Soltan Beyad   +1 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Les espèces exotiques envahissantes, pour une remise en cause des paradigmes écologiques Invasive species: challenging the ecological paradigms [PDF]

open access: yesSciences, Eaux & Territoires, 2012
Les espèces exotiques font couler beaucoup d'encre et sont souvent présentées de manière négative. On les accuse de devenir envahissantes, d'entrer en concurrence avec les espèces autochtones, d'entraîner un dysfonctionnement des écosystèmes, et d'avoir ...
LEVEQUE, Christian, TABACCHI, Eric, MENOZZI, Marie-Jo
doaj  

Novel predictors of neurosyphilis among HIV-negative syphilis patients with neurological symptoms: an observational study

open access: yesBMC Infectious Diseases, 2017
Background Known predictors of neurosyphilis were mainly drawn from human immunodeficiency virus (HIV)-infected syphilis patients, which may not be applicable to HIV-negative populations as they have different characteristics, particularly those with ...
Yao Xiao   +12 more
doaj   +1 more source

Judges and Economic Reasoning in Competition Law

open access: yes, 2008
Economic reasoning is a distinctive feature of competition law. At first sight, it may appear as foreign to judges. A closer analysis, however, shows that there is no conflict of logic between economic and judicial reasoning.
Sibony, Anne-Lise
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The antitrust legal regulation of the gas industry in the European Union

open access: yesRUDN Journal of Law, 2016
In the article, the author focuses primarily on the general rules of EU antimonopoly regulation, inter alia: the dominant position, the anti-competitive agreements and the State assistance. The author also specifies of special features of the regulation,
Aleksandr Konstantinovich Volkov
doaj  

Home - About - Disclaimer - Privacy