Results 111 to 120 of about 626,798 (385)

Aligned Fibronectin Microenvironment Temporally Facilitates Profibrotic Fibroblast Activation via Integrin α5β1

open access: yesAdvanced Science, EarlyView.
Compared to a healthy random nanofibrous fibronectin microenvironment, a fibrotic aligned nanofibrous fibronectin microenvironment employs a specific integrin, α5β1 integrin, to activate early pro‐fibrotic fibroblast behaviors and later fibrotic fibroblast tissue formation with cell/F‐actin alignment, α‐SMA expression, and cell‐driven aligned ...
Doğuhan Beyatlı   +3 more
wiley   +1 more source

Diallyl Disulfide Mitigates LPS-Induced Inhibition of Osteogenic Differentiation and Alleviates Inflammatory Bone Loss via PI3K/AKT Signaling Pathway

open access: yesDrug Design, Development and Therapy
Jinze Wu,1,* Debin Guo,2,* Yimin Du,3,* Zi Wang,4,* Shidan Li,1 Honghao Xu,1 Xiang Chu,1 Xiaowen Gao,5 Lei Li,6 Jun Fei1 1War Trauma Medical Center, State Key Laboratory of Trauma and Chemical Poisoning, Army Medical ...
Wu J   +9 more
doaj  

Lithium Poisoning

open access: yesJournal of Intensive Care Medicine, 2016
Lithium is a commonly prescribed treatment for bipolar affective disorder. However, treatment is complicated by lithium’s narrow therapeutic index and the influence of kidney function, both of which increase the risk of toxicity. Therefore, careful attention to dosing, monitoring, and titration is required.
Baird-Gunning, Jonathan   +4 more
openaire   +5 more sources

Mass‐Transport–Engineered CCM Architecture Employing MPL‐Free Carbon Paper and Graphene‐Coated Ni Foam Channels for High‐Temperature PEM Fuel Cells

open access: yesAdvanced Science, EarlyView.
A CCM‐based architectural strategy is introduced for high‐temperature PEM fuel cells, enabling MPL‐free carbon paper gas diffusion layers via decal‐transfer processing. By co‐engineering the CCM, GDL, and a G‐foam flow field, oxygen transport is enhanced while phosphoric‐acid leakage is suppressed, resulting in high power density and stable operation ...
Seongmin Cho   +6 more
wiley   +1 more source

Targeted Thrombolysis via CCR2‐Engineered Macrophage‐Mimicking Microbubbles Safely Ablates Venous, Arterial, and Microvascular Thrombosis

open access: yesAdvanced Science
The clinical management of thrombosis, a primary cause of death worldwide, is hampered by the limitations of current thrombolytic agents, including short half‐life and high risk of off‐target bleeding.
Buying Li   +8 more
doaj   +1 more source

Tailored Catalytic Microenvironments Enable Efficient Electrochemical Ammonia Production

open access: yesAdvanced Science, EarlyView.
This study shows that Co2+ substitution in inverse spinel FeFeCoO4 constructs an integrated catalytic microenvironment for efficient nitrate‐to‐ammonia reduction. Jahn–Teller distortion activates Fe sites for *H generation, while hard–soft acid–base regulated dual‐metal sites optimize proton‐coupled electron transfer and intermediate adsorption ...
Qi Zhang   +8 more
wiley   +1 more source

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