Results 151 to 160 of about 626,798 (385)

α1A-adrenergic receptor activation ameliorates fragmented spatial exploration by improving astrocyte-neuronal coupling in the medial entorhinal cortex of Alzheimer's disease mice

open access: yesNeurobiology of Disease
Spatial exploration is fundamental to the construction of internal cognitive maps, yet the mechanisms underlying its fine-scale microstructural disruption in Alzheimer's disease (AD) remain elusive. The medial entorhinal cortex layer II (MECII) serves as
Fengjuan Wu   +15 more
doaj   +1 more source

Adaptive Coordination Engineering for Efficient and Robust H2 Release

open access: yesAdvanced Science, EarlyView.
β‐H elimination is a pivotal but challenging step in homogeneous formic acid dehydrogenation reactions due to strict hydride‐metal matching. By using a rationally designed Pd1Ag2 bimetallic system with adaptive Pd1‐Ag2/L2 coordination and formate bridges, it enables boosted formic acid dehydrogenation under ambient air (7.7 times higher than a Pd ...
Xiaolin Jiang   +8 more
wiley   +1 more source

Pharmaceutical Manipulation of Mitochondrial F0F1‐ATP Synthase Enables Imaging and Protection of Myocardial Ischemia/Reperfusion Injury Through Stress‐induced Selective Enrichment

open access: yesAdvanced Science
To rescue ischemic myocardium from progressing to myocardial infarction, timely identification of the infarct size and reperfusion is crucial. However, fast and accurate identification, as well as the targeted protection of injured cardiomyocytes ...
Zelin Chen   +14 more
doaj   +1 more source

Childhood Lead Poisoning Prevention Program Community Awareness Pilot : CLPPP CAP

open access: yes
Lead is a highly toxic substance, and exposure to lead can cause a range of adverse health effects. Children as well as adults can be sick from the effects of lead poisoning, but lead poisoning is much more frequent in children than in adults.

core  

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu   +13 more
wiley   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

open access: yesAdvanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng   +12 more
wiley   +1 more source

Clorine poisoning

open access: yes
Health workers should be aware of rumors that drinking chlorine or disinfectant solutions could cure or prevent Ebola virus disease (Ebola). Chlorine is NOT a cure for Ebola. No one should ever drink chlorine or disinfectant solutions containing chlorine.

core   +1 more source

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