Results 51 to 60 of about 835,873 (364)

Toxicity and urinary metabolites of α-amanitin in mice

open access: yesZhongguo gonggong weisheng, 2022
ObjectiveTo explore toxicity and urinary metabolites of α-amanitin in mice with a 21-day toxicological experiment. MethodsTwenty ICR male mice were randomly divided into a control (n = 5) and three median lethal dose (LD50) groups (5 in each group) with ...
Zhi-jun WU, Wen-jin ZHAO, Hai-jiao LI
doaj   +1 more source

Impact of paracetamol pack size restrictions on poisoning from paracetamol in England and Wales: an observational study.

open access: yes, 2005
BACKGROUND: About 500 drug poisoning deaths involving paracetamol (acetaminophen) occur every year in England and Wales. To reduce the number of deaths, regulations were introduced in 1998 to restrict the sale of paracetamol.
Griffiths, Clare   +2 more
core   +1 more source

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Epidemiological study of drug intoxication in children [PDF]

open access: yes, 2006
Unintentional drug intoxication is still a major cause of morbidity and mortality in young children. In order to study the epidemiological pattern of childhood drug poisoning in Golestan province, all cases diagnosed with poisoning from 1997 to 2002 in ...
Cheraghali, F., Taymori, M.
core  

Phase transitions and crossovers in reaction-diffusion models with catalyst deactivation

open access: yes, 2009
The activity of catalytic materials is reduced during operation by several mechanisms, one of them being poisoning of catalytic sites by chemisorbed impurities or products.
Froment G. F.   +3 more
core   +1 more source

Design and Implementation of a Review Management System in the Field of Medicine and Health [PDF]

open access: yesمجله انفورماتیک سلامت و زیست پزشکی, 2023
Introduction: The increasing growth of science and specialized articles in various fields, especially in health and treatment, has faced researchers with the challenge of keeping up with this progress.
Mehran Modares Torbati   +5 more
doaj  

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

Nanomaterial-Based Repurposing of Macrophage Metabolism and Its Applications

open access: yesNano-Micro Letters
Highlights A large-scale metabolic adaptation in M1-polarized macrophages compared with M2 macrophages, along with multiple altered metabolite parameters that can serve as potential targets, have been discussed.
Tingting Meng   +9 more
doaj   +1 more source

Lactiplantibacillus plantarum ameliorated the negative effects of a low-protein diet on growth performance, antioxidant capacity, immune status, and gut microbiota of laying chicks

open access: yesFrontiers in Microbiology
This experiment was conducted to investigate the effects of adding Lactiplantibacillus plantarum to a low-protein diet on the growth performance, ability immune status, and intestinal microbiota of 0–21-day-old layer chickens.
Lele Hou   +5 more
doaj   +1 more source

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski   +13 more
wiley   +1 more source

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