Results 71 to 80 of about 290,076 (302)

A pilot study reveals plasma metabolomic and lipidomic signatures of mustard lung disease

Scientific Reports
Accurately diagnosing mustard lung disease (MLD) presents a significant challenge due to its intricate nature and overlapping clinical features with other pulmonary conditions.
B. Fatemeh Nobakht M. Gh., Hasan Bagheri, Uri Keshet, Mostafa Ghanei   +3 more
doaj   +1 more source

Clinical features of toxic encephalopathy induced by 1,2-dichloroethane

Frontiers in Toxicology
Introduction1,2-Dichloroethane (1,2-DCE) is a highly toxic industrial organic solvent that can cause acute toxic encephalopathy through occupational exposure, with underreported clinical data in English literature. To explore the clinical characteristics
Yuquan Chen, Yuqiang Lin, Yifan Ye, Meiwen Xie, Jiaqi Chen, Zhiqian Yang, Zhi Wang   +6 more
doaj   +1 more source

Childhood Lead Poisoning Prevention Program (CLPPP) 30th anniversary [PDF]

CDC has a long-standing role in childhood lead poisoning prevention. In 2021, CDC\u2019s Childhood Lead Poisoning Prevention Program (CLPPP) commemorates 30 years of funding state and local childhood lead poisoning prevention programs to eliminate ...

core  

Pesticide Poisoning of Farm Workers : Implications of Blood Test Results from Vietnam

, 2005
In this paper, the authors have assessed the incidence and determinants of pesticide poisoning among rice farmers in Vietnam's Mekong Delta. Blood cholinesterase tests suggest that the incidence of poisoning from exposure to organophosphates and ...
Dasgupta, Susmita, Lam, Nhan Thi, Xuyen, Khuc, Meisner, Craig, Wheeler, David   +4 more
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Targeting the NLRP3 in macrophages contributes to senescence cell clearance in radiation-induced skin injury

Journal of Translational Medicine
Background The persistent accumulation of senescence cells is one of the characteristics of radiation-induced skin injury (RISI), leading to fibrosis and impaired healing.
Gaoyu Liu, Yan Chen, Shijie Dai, Gang Wu, Fulong Wang, Wanchao Chen, Lingling Wu, Peng Luo, Chunmeng Shi   +8 more
doaj   +1 more source

Efficacy and safety of transcutaneous electrical nerve stimulation in the treatment of moderate-to-severe itch after burns on limbs (TE-ITCH): protocol for a multicentre, randomised, placebo-controlled clinical trial

BMJ Open
Introduction Itching is a common and distressing clinical manifestation following burns, which severely impairs patient quality of life. Current pharmacotherapy for post-burn pruritus is limited by low efficacy and frequent side effects.
Ning Li, Ling Zhou, Wei Zhu, Lei Cao, Xue Heng, Linjun Li, Gaoxing Luo, Haisheng Li   +7 more
doaj   +1 more source

Lithium Poisoning

Journal of Intensive Care Medicine, 2016
Lithium is a commonly prescribed treatment for bipolar affective disorder. However, treatment is complicated by lithium’s narrow therapeutic index and the influence of kidney function, both of which increase the risk of toxicity. Therefore, careful attention to dosing, monitoring, and titration is required.
Baird-Gunning, Jonathan, Lea-Henry, Tom N, Hoegberg, Lotte, Gosselin, Sophie, Roberts, Darren   +4 more
openaire   +5 more sources

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source

Factors associated with adverse clinical features in patients presenting with non-fatal self-poisoning

, 2011
Background: Drug overdose or self poisoning is an important reason for an ambulance service response. We aimed to undertake a preliminary investigation into the pattern of drug overdose presenting to one ambulance service and factors associated with ...
Deborah Shaw (16053866), Anne Spaight (17186986), Mohammad Iqbal (17160598), Stella May Gwini (13356477), Niro Siriwardena (17167375)   +4 more
core   +3 more sources