Results 81 to 90 of about 183,766 (238)

Astrocytic α7-nicotinic acetylcholine receptors mediate pain information processing and perception

Neurobiology of Disease
The astrocyte–neuron network in the primary somatosensory cortex (S1) responds dynamically to pain stimuli and plays a pivotal role in pain processing.
Teng Teng, Shaofan Yang, Jin Li, Haoyu Wang, Fengjuan Wu, Yong He, Jihua Fan, Hongwei Shi, Mingzhu Huang, Xiang Zhou, Ying Liu, Mingyue Gong, Chuanyan Yang, Huiquan Wang, Zhenlu Cai, Hongli Li, Kuan Zhang   +16 more
doaj   +1 more source

Photoelectric‐Coupled Ferroelectric Heterojunctions for Ultrahigh NO2 Sensing With Polarization‐Memory‐Assisted Interfacial Modulation

Advanced Science, EarlyView.
This study demonstrates a Bi2WO6/SrBi2Ta2O9 heterojunction where light‐driven ferroelectric polarization reversal couples with persistent photoconductivity, enabling exclusive NO2 selective room‐temperature sensing. The device achieves a two‐order‐of‐magnitude sensitivity enhancement over an unpolarized device, a sub‐ppb detection limit, and robust ...
Liping Tan, Xuefeng Hu, Ming Zhou, Weiwei Qing, Along Li, Zilong Wang, Mudan Feng, Shuang Zhao, Xiaoliang Wang, Peipei Li, Yali Bi, Wei Zhang   +11 more
wiley   +1 more source

Atomic‐Level CuOx‐CoOx‐Pd Interfacial Engineering Enables Hierarchical Synergy for High‐Efficiency ORR Pathways and Boosted Power Output in Alkaline Fuel Cells

Advanced Science, EarlyView.
Atomically dispersed CuOx (CPCu‐1) forms isolated Cu–Ov sites that enable defect‐mediated O2 activation and fast electron/proton transfer via interfacial synergy. In contrast, thick CuOx clusters (CPCu‐10) promote a surface‐adsorption‐controlled pathway with intermediate accumulation, highlighting a mechanism switch from interfacial activation to ...
Yang‐Yang Hsu, Ching‐Hua Fan, Kuan‐Wen Wang, Kuang‐Kuo Wang, Nozomu Hiraoka, Hirofumi Ishii, Ting‐Shan Chan, Po‐Chun Chen, Tsan‐Yao Chen   +8 more
wiley   +1 more source

Adaptive Coordination Engineering for Efficient and Robust H2 Release

Advanced Science, EarlyView.
β‐H elimination is a pivotal but challenging step in homogeneous formic acid dehydrogenation reactions due to strict hydride‐metal matching. By using a rationally designed Pd1Ag2 bimetallic system with adaptive Pd1‐Ag2/L2 coordination and formate bridges, it enables boosted formic acid dehydrogenation under ambient air (7.7 times higher than a Pd ...
Xiaolin Jiang, Xiaoyang Yan, Shenglong Jiang, Hongdan Zhu, Heng Wang, Xiaopeng Li, Xiaochun Zhou, Mingdong Zhou, Qian Peng   +8 more
wiley   +1 more source

Dexmedetomidine alleviates sepsis-associated acute kidney injury by inhibiting renal tubular ferroptosis via JNK/MAPK–LCN2 pathway

European Journal of Medical Research
Background Sepsis-associated acute kidney injury (SA-AKI), one of the most common complications of sepsis, significantly prolongs hospitalization, increases mortality, and elevates risks of cardiovascular events and chronic kidney disease.
Boyang Liu, Shengxiang Ao, Li Luo, Lin Qiao, Tianyin Kuang, Hongyan Xiao, Jing Zhou, Shuangqin Yin, Huaping Liang, Fen Li, Weihong Dai, Junyu Zhu   +11 more
doaj   +1 more source

Biodegradation of ZEN by Bacillus mojavensis L-4: analysis of degradation conditions, products, degrading enzymes, and whole-genome sequencing, and its application in semi-solid-state fermentation of contaminated cornmeal

Frontiers in Microbiology
Zearalenone (ZEN), a naturally occurring estrogenic mycotoxin prevalent in cereals and animal feed, poses significant challenge to livestock industry owing to its detrimental effects on animal reproduction.
Jiagao Chang, Wenxuan Dong, Shansong Gao, Lele Hou, Jihong Dong, Huiling Qiu, Fu Chen   +6 more
doaj   +1 more source

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source

Threats and responses: a qualitative study on the early postoperative ambulation experiences of older patients with kinesiophobia after total hip arthroplasty in Western China

BMC Musculoskeletal Disorders
Objective To understand the authentic early postoperative ambulation experiences of older patients with kinesiophobia following total hip arthroplasty, with the aim of developing early rehabilitation intervention programs for this group.
Yu Xie, Chunmei Li, Xiaoli He, Yan Luo, Shuying Liu, Lianyang Zhang, Qingshan Guo, Siru Zhou, Yang Li, Yu Luo   +9 more
doaj   +1 more source

Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction

Advanced Science, EarlyView.
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng, Jing Sheng, Ben Niu, Wenjuan Fu, Yingjie Yang, Zuowei Xie, Shuang Xie, Yunxuan He, Meilin Gong, Jue Wang, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

Astrocytes in the medial entorhinal cortex are required for spatial exploration

Cell Reports
Summary: Exploring the environment is essential for survival and has traditionally been attributed primarily to neuronal functions. However, the role of astrocytes in regulating exploratory behaviors remains poorly understood.
Mingzhu Huang, Zhiqi Yang, Haoyu Wang, Shaofan Yang, Jin Li, Shanshan Liang, Teng Teng, Chuanyan Yang, Mingyue Gong, Han Qin, Xingyi Li, Xiaowei Chen, Xiang Liao, Kuan Zhang   +13 more
doaj   +1 more source