Results 11 to 20 of about 489,664 (384)

Acute occupational exposures reported to the Dutch Poisons Information Center: a prospective study on the root causes of incidents at the workplace

Journal of Occupational Medicine and Toxicology, 2022
Background Hazardous substances at the workplace can cause a wide variety of occupational incidents. This study aimed to investigate the nature and circumstances of acute occupational intoxications reported to the Dutch Poisons Information Center ...
Anja P. G. Wijnands, Irma de Vries, Tim Verbruggen, Maxim P. Carlier, Dylan W. de Lange, Saskia J. Rietjens   +5 more
doaj   +1 more source

Analysis of poisons and drugs in entomological specimens for forensic applications: a review

Arab Journal of Basic and Applied Sciences, 2023
Certain poisons and drugs can influence the growth and developmental patterns of necrophagous species, possibly affecting the accuracy of the postmortem interval (PMI) estimation.
Sri Adelila Sari, Nor Wajihan Muda, Mohamad Afiq Mohamed Huri, Aemi Syazwani Abdul Keyon, Aida Rasyidah Azman, Naji Arafat Mahat   +5 more
doaj   +1 more source

Topoisomerase II Poisons: Converting Essential Enzymes into Molecular Scissors.

Biochemistry, 2021
The extensive length, compaction, and interwound nature of DNA, together with its controlled and restricted movement in eukaryotic cells, create a number of topological issues that profoundly affect all of the functions of the genetic material ...
K. R. Vann, Alexandria A. Oviatt, N. Osheroff   +2 more
semanticscholar   +1 more source

An adolescent female with intentional ingestion of a large amount of metformin requiring extracorporeal membrane oxygenation and continuous renal replacement therapy [PDF]

Pediatric Emergency Medicine Journal, 2023
Acute overdose of metformin can show potentially fatal lactic acidosis. Management should be directed towards close monitoring of renal function and hemodynamics.
Kaila Lessner, Lauren McKinney, Ilana Anderson, Chie-Youn Shih, J. Bryan Carmody, Meaghan Dominy   +5 more
doaj   +1 more source

Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms

bioRxiv, 2021
Topoisomerase II (Top2) unlinks chromosomes during vertebrate DNA replication. Top2 ‘poisons’ are widely-used chemotherapeutics that stabilize Top2 complexes on DNA, leading to cytotoxic DNA breaks.
Sabrina X Van Ravenstein, Kavi P M Mehta, Tamar Kavlashvili, J. A. Byl, R. Zhao, N. Osheroff, D. Cortez, James M. Dewar   +7 more
semanticscholar   +1 more source

La saveur du cœur et l’amertume du corps

Revue d'ethnoécologie, 2023
In light of the recent ethnographic production on the indigenous Arawá peoples and the research in historical ecology dedicated to the lands of the Juruá-Purus interfluve, this article proposes a reflection on plant poisons, hunting and fishing, based on
Karen Shiratori, Daniel Cangussu
doaj   +1 more source

Medicines Policy and Drugstores in Serbia Until the Second World War [PDF]

Токови историје, 2023
The paper analyzes the effects of medicines policy on the functional separation of pharmacy and drugstore businesses from the early 19th century to the Second World War.
Jasmina Arsić, Dušanka Krajnović
doaj   +1 more source

Natural Polyphenols—Resveratrol, Quercetin, Magnolol, and β-Catechin—Block Certain Aspects of Heroin Addiction and Modulate Striatal IL-6 and TNF-α

Toxics, 2023
We have examined the effects of four different polyphenols in attenuating heroin addiction using a conditioned place preference (CPP) paradigm. Adult male Sprague Dawley rats received heroin (alternating with saline) in escalating doses starting from 10 ...
Shaimaa ElShebiney, Rania Elgohary, Marwa El-Shamarka, Noha Mowaad, Osama A. Abulseoud   +4 more
doaj   +1 more source

From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery

Frontiers in Pharmacology, 2020
Animal poisons and venoms are comprised of different classes of molecules displaying wide-ranging pharmacological activities. This review aims to provide an in-depth view of toxin-based compounds from terrestrial and marine organisms used as diagnostic ...
Karla C F Bordon, C. Cologna, Elisa Correa Fornari-Baldo, E. Pinheiro-Junior, F. Cerni, F. G. Amorim, F. A. P. Anjolette, F. Cordeiro, G. Wiezel, I. Cardoso, I. Ferreira, I. S. de Oliveira, Johara Boldrini-França, M. Pucca, Mateus Amaral Baldo, E. Arantes   +15 more
semanticscholar   +1 more source

The Literary Works of Miguel de Cervantes from the Perspective of Psychopharmacology: The Four Aspects of Phármakon

Taiwanese Journal of Psychiatry, 2021
Background: Miguel de Cervantes (1547–1617) was a Spanish writer, who has often been considered as the greatest writer in the Spanish language and one of the world's outstanding novelists.
Francisco Lopez-Munoz
doaj   +1 more source