Results 51 to 60 of about 489,664 (384)
The potential role and application of PARP inhibitors in cancer treatment [PDF]
, 2009 Background: Since many anti-cancer agents act by inflicting DNA damage on tumour cells, there is increasing interest in the use of inhibitors of DNA repair to increase the cytotoxicity of these agents.
Chalmers, Anthony J
core +2 more sources
Zinc oxide calcium silicate composite attenuates acute tramadol toxicity in mice
BMC Pharmacology and Toxicology, 2023 Background Seizures are considered to be the most common symptom encountered in emergency- rushed tramadol-poisoned patients; accounting for 8% of the drug-induced seizure cases.
Shaimaa A. ElShebiney +4 more
doaj +1 more source
Why Do We Worry about Trace Poisons? [PDF]
, 1996 Dr. Mazur relates how protests by the political left against nuclear tests and by the political right against fluoridation set the stage for Silent Spring to move the public toward being concerned about latent ...
Mazur, Allan
core +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Frontiers in Medicine, 2023 Pregabalin (PB) overdose causes mild symptoms and coma is rarely seen unless the patient has also ingested sedatives and/or has preexisting renal disease.
Visti Torbjørn Nielsen +3 more
doaj +1 more source
Chemical narcosing of fish in northern Cross River [PDF]
, 1986 Chemical narcosing of fish was found to be one of the fishing techniques used for harvesting fish stocks in the northern Cross River, Cross River State, Nigeria. The preparation of the fish poison is described.
Lebo, P., Udolisa, R.E.K.
core
Nature Communications, 2017 Animals using toxic peptides and proteins for predation or defense typically depend on specialized morphological structures, like fangs, spines, or a stinger, for effective intoxication.
Constantijn Raaymakers +12 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra +17 more
wiley +1 more source
Clinical Recommendations on Emergency Medical Care Rendering to Children with Acute Intoxication
Педиатрическая фармакология, 2016 The article is dedicated to the issue of intoxication in children. Acute accidental intoxication appears to be especially relevant for pediatric practice. Drugs, various chemicals frequently used in everyday life and in farming, as well as animal poisons,
A. A. Baranov +6 more
doaj +1 more source