Advanced Science, EarlyView.Synaptic vesicle (SV) motion and exocytosis dynamics in the presynaptic terminals of live neurons are intimately linked to synaptic transmission during neuronal activity. In this work, it is revealed that, during electrical stimulation, SVs located farther from their fusion sites exhibit greater straightness and experience larger mean forces directed ...
Gyunam Park +7 more
wiley +1 more source
Forecasting the Monkeypox Outbreak Using Limited Data: A Case Study of Thailand. [PDF]
Interdiscip Perspect Infect DisShuaib SE +3 more
europepmc +1 more source
Single‐Target Pairing System (StarPair) for Large‐Scale Interrogation of Cell–Cell Interactions
Advanced Science, EarlyView.This work presents a single‐target pairing system, StarPair, enabling cell–cell interaction studies by target combination in droplets. StarPair offers superior pairing efficiencies over 95% and operation frequencies of 105 pairs per 9.5 h for two‐target pairing, allowing large‐scale interrogation of immune cell‐cancer cell interactions and precise ...
Tianjiao Mao +6 more
wiley +1 more source
Total hip arthroplasty in Italy: an observational, population-based study on surgical volume growth from 2001 to 2023 and forecasts until 2050 with six different statistical models. [PDF]
J Orthop TraumatolCiminello E +11 more
europepmc +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Advanced Science, EarlyView.Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
Spike count analysis for multiplexing inference (SCAMPI). [PDF]
J Comput NeurosciChen Y, Groh JM, Tokdar S.
europepmc +1 more source
Advanced Science, EarlyView.IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu +9 more
wiley +1 more source
Extending ImmunoSpot® Assays' Sensitivity for Detecting Rare Antigen-Specific B Cells to One in a Million-And Possibly Lower. [PDF]
Vaccines (Basel)Kirchenbaum GA +4 more
europepmc +1 more source
Stretchable Curvature Sensors for Motion Capture with Bending‐Stretching Coupling Deformation
Advanced Science, EarlyView.Stretchable curvature sensors based on a wavy symmetric stacked‐layer structure (WSSLS) enable decoupled bending‐stretching detection with high linearity, repeatability, and durability. Integrated into smart gloves, the sensors achieved precise motion capture and human‐robot interaction, with slip‐simulation tests demonstrating a remarkable 93.6 ...
Tairan Wang +9 more
wiley +1 more source
3D-Printed Titanium and Standalone Lateral Lumbar Interbody Fusion. [PDF]
Global Spine JDaungsupawong H, Wiwanitkit V.
europepmc +1 more source