Results 51 to 60 of about 466,499 (265)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Open Access Data in Polar and Cryospheric Remote Sensing
Remote Sensing, 2014 This paper aims to introduce the main types and sources of remotely sensed data that are freely available and have cryospheric applications. We describe aerial and satellite photography, satellite-borne visible, near-infrared and thermal infrared sensors,
Allen Pope +3 more
doaj +1 more source
Regional polar warming linked to poleward moisture transport variability
Environmental Research: Climate, 2023 Polar warming, ice melt and strong precipitation events are strongly affected by episodic poleward advection of warm and moist air (Woods and Caballero 2016 J. Clim. 29 4473–85; Wille et al 2019 Nat. Geosci.
Richard Bintanja +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Sustainable Tourism and Natural Resource Conservation in the Polar Regions: An Editorial
Resources, 2017 This editorial provides an introduction to the special issue of Resources on Sustainable Tourism and Natural Resource Conservation in the Polar Regions, which proceeds the fifth bi-annual conference of the International Polar Tourism Research Network ...
Edward Huijbens, Machiel Lamers
doaj +1 more source
Geophysical Research Letters, 2022 In the original hypothesis of ice in lunar polar cold traps, it was presumed that meteoritic water acquired by the lunar surface would be concentrated in cold traps by exospheric lateral transport. That supposition is proven to be false by the absence of
R. R. Hodges, W. M. Farrell
doaj +1 more source
Cell polarity: Par for the polar course [PDF]
Current Biology, 1997 The nematode PAR-1 gene is required for asymmetric cell divisions during development. Recently identified mammalian Par-1 homologues are kinases that phosphorylate microtubule-associated proteins; their overexpression disrupts the microtubule cytoskeleton, and alters cellular structure and organization.
Nelson, W.James, Grindstaff, Kent K.
openaire +2 more sources