Results 91 to 100 of about 49,266 (284)

Polar Amplification: Is Atmospheric Heat Transport Important?

, 2013
Surface albedo feedback is widely believed to be the principle contributor to polar amplification. However, a number of studies have shown that coupled ocean-atmosphere models without ice albedo feedbacks still produce significant polar amplification in ...
Jackson, Craig, Alexeev, Vladimir
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Simple Estimates of Polar Amplification in Moist Diffusive Energy Balance Models

, 2018
Diffusive energy balance models (EBMs) that use moist static energy, rather than temperature, as the thermodynamic variable to determine the energy transport provide an idealized framework to understand the pattern of radiatively forced surface warming.
Matthew Henry, Timothy M. Merlis
core   +1 more source

Spatial Patterns of Modeled Climate Feedback and Contributions to Temperature Response and Polar Amplification [PDF]

, 2011
Spatial patterns of local climate feedback and equilibrium partial temperature responses are produced from eight general circulation models with slab oceans forced by doubling carbon dioxide (CO2).
Forster, PM, Crook, JA, Julia A. Crook, Nicola Stuber, Stuber, N, Piers M. Forster   +5 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Tropical ocean-atmosphere controls on inter-annual climate variability in the Cretaceous Arctic

, 2011
The first annually resolved sedimentary record from the Cretaceous is used to develop time series of inter-annual and decadal scale climate variability from the Arctic Ocean.
Kemp, Alan E.S., Heiko Pälike, Davies, Andrew, Pälike, Heiko, Alan E. S. Kemp, Andrew Davies   +5 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Bimodality of hemispheric winter atmospheric variability via average flow tendencies and kernel EOFs

Tellus: Series A, Dynamic Meteorology and Oceanography, 2019
The topic of the existence of planetary winter circulation regimes has gone through a long debate. This article contributes to this debate by investigating nonlinearity in a 3-level quasi-geostrophic model and the Japanese JRA-55 reanalysis.
A. Hannachi, W. Iqbal
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source