Results 111 to 120 of about 52,059 (298)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Transcriptome responses to benzo[a]pyrene in liver slices of sub-arctic fish species
Frontiers in Marine ScienceDue to the expanding oil-related activities, the arctic and sub-arctic marine environments are increasingly vulnerable to oil-related pollution such as accidental oil spills. These cold-water ecosystems harbor many fish species that are both ecologically
Nadja R. Brun +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Известия ТИНРО, 2014 New eco-ethological data on the Anadyr stock of beluga whales are presented based on 14-year (2000-2013) studies by methods of satellite tracking telemetry, multi-spectral aerial surveys and genetic analysis, as well as traditional and ecosystem-based ...
Denis I. Litovka, Ludmila N. Khitzova
doaj +1 more source
Ecosystem-based Management for Protected Species in the North Pacific Fisheries [PDF]
, 2011 In the North Pacific Ocean, an ecosystem-based fishery management approach has been adopted. A significant objective of this approach is to reduce interactions between fishery-related activities and protected species.
Heltzel, Jeannie M. +2 more
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Polar Coded HARQ Scheme with Chase Combining
, 2014 A hybrid automatic repeat request scheme with Chase combing (HARQ-CC) of polar codes is proposed. The existing analysis tools of the underlying rate-compatible punctured polar (RCPP) codes for additive white Gaussian noise (AWGN) channels are extended to
Chen, Kai +3 more
core +1 more source
DNA metabarcoding reveals surprisingly diverse diet in under-ice polar cod during autumn
Polar BiologyAbstract Polar cod (Boreogadus saida) functions as a key species in the Arctic food web and is one of the most abundant Arctic fishes. Despite its ecological importance, the feeding ecology of juveniles sampled under the sea ice is unknown.
Sarah M. Maes +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Quality changes of Moringa oleífera, variety Mbololo of Kenya, seed oil during frying.
Grasas y Aceites, 1999 The frying performance of Moringa oleífera variety Mbololo of Kenya seed oil (produced by cold pressure, extraction with n-hexane and a mixture of chloroform-methanol) was studied especially as regards repeated frying operations.
John Tsaknis +4 more
doaj +1 more source