Results 91 to 100 of about 2,094,495 (266)

Modelling polar bear maternity den habitat in east Svalbard

open access: yes, 2020
We evaluated a novel tool that predicts possible maternity den habitat of the polar bear (Ursus maritimus) based on a physical snow transport model, a digital terrain model and weather data.
Aars, Jon   +2 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Late Pleistocene fossil find in Svalbard: the oldest remains of a polar bear (Ursus maritimus Phipps, 1744) ever discovered

open access: yes, 2009
During recent fieldwork in Svalbard, a well preserved subfossil left mandible of a polar bear (Ursus maritimus Phipps, 1774) was discovered. A 14C age determination shows that it is older than 45 Ky (kilo-years), and an age determination with infrared ...
Wiig, Øystein, Ingólfsson, Ólafur
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Review of The expeditions of the first International Polar Year 1882–83, by William Barr

open access: yes, 2009
It is probably safe to assume that no readers of Polar Research are unaware that we have just come through a fourth International Polar Year (IPY). All science is, or should be, based on the previous achievements of others, and thus the experiences and ...
Barr, Susan
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Comparison of Water Pretreatment Devices for the Measurement of Polar Odorous Compounds

open access: yesApplied Sciences, 2019
A major problem of measuring polar compounds in the air is water vapor. Therefore, it is important to use a water pretreatment device prior to sampling and analysis.
Joo-Yeon Lee   +7 more
doaj   +1 more source

Review of Legacies and change in polar sciences: historical, legal and political reflections on the International Polar Year, edited by JM Shadian & M Tennberg

open access: yes, 2010
The International Polar Year (IPY) of 2007–09 was an international scientific enterprise that encompassed all polar regions, and built on the legacies bequeathed by earlier endeavours stretching back to the late 19th century.
Dodds, Klaus
core   +1 more source

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