Results 81 to 90 of about 201,320 (259)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Polar Compounds Dominate in Vitro Effects of Sediment Extracts
, 2016 Sediment extracts from three polluted sites of the river Elbe basin were fractionated using a novel online fractionation procedure. Resulting fractions were screened for mutagenic, aryl hydrocarbon receptor (AhR)-mediated, transthyretin (TTR)-binding ...
Jan Vondracek (2223460) +13 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
, 1995 P(論文)Arctic aerosol samples were collected at Alert (82.5°N, 62.3°W) in February to June, 1991 using a high volume air sampler and quartz fiber filter, and were studied for total carbon and nitrogen, water soluble organic carbon, and individual ...
カスカベ, ヒデキ / +4 more
core +1 more source
Comparison of Water Pretreatment Devices for the Measurement of Polar Odorous Compounds
Applied Sciences, 2019 A major problem of measuring polar compounds in the air is water vapor. Therefore, it is important to use a water pretreatment device prior to sampling and analysis.
Joo-Yeon Lee +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Distribution of selenium binding proteins in liver from two species of penguins from Bouvetøya
, 1991 Chinstrap penguin Pygoscelis antarctica and macaroni penguin Eudyptes chrysolophus were collected at Bouvettfya in the south Atlantic. The average hepatic selenium levels for the two species were 6.6 ± 2.9 and 23.6 ± 3.4 ng/g wet weight (P < 0.001 ...
Bech, C. +3 more
core +1 more source
Effectiveness of added natural antioxidants in sunflower oil
Grasas y Aceites, 2005 The antioxidant activity of α- and δ-tocopherol, citric acid, ascorbic acid and ascorbyl palmitate was investigated in sunflower oil containing naturally occurring tocopherol.
Amalia A. Carelli +2 more
doaj +1 more source
Integrated Supercritical Fluid Extraction and Pre-Formulation Process of Punica granatum L. Pericarp Polar Compounds. [PDF]
Molecules, 2023 Atwi-Ghaddar S +2 more
europepmc +1 more source