Results 51 to 60 of about 2,094,495 (266)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Trichinella sp. in polar bears from Svalbard, in relation to hide length and age
, 2010 Diaphragm and masseter muscles from 376 polar bears ((irsur maririmus), 252 ringed seals (Phocn hispida), 84 bearded seals (Erignarhus barbarus), and 77 arctic foxes (Alopex lagopus) from Svalbard were examined for Trichinelln.
Larsen, Thor, Kjos-Hanssen, Bjørn
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Antioxidants, 2021 Avocado oil is considered a highly prized food due to its nutritional contribution. On the other hand, Aristotelia chilensis (Molina) Stuntz (Elaeocarpaceae), common name “maqui”, is an endemic fruit in Chile, well known for its exceptional antioxidant ...
Marcos Flores +7 more
doaj +1 more source
Polar bears killed in Svalbard 1987–1992
, 1993 A total of 26 polar bears have been killed in Svalbard since January 1987. Fifteen of these cases were self defense, four precautionary measures, six acts of mercy and one unknown.
Gjertz, Ian +2 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The interplay of global and polar regimes
, 1999 The growing salience of interactions between the functionally broad but geographically narrow regimes for the polar regions and the geographically broad but functionally specific regimes emerging to deal with global environmental changes directs ...
Young, Oran R.
core +1 more source
Polar federated search: New infrastructure to support the polar community
, 2023 This paper reports how the World Data System International Technology Office (WDS-ITO) has contributed resources in the Polar Research Data Management community.
Melinda Minch +5 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source