Results 91 to 100 of about 130,570 (300)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

DETERMINATION OF SIZE OF THE EMITTING REGION IN ECLIPSING CATACLYSMIC VARIABLE STARS

open access: yesOdessa Astronomical Publications, 2014
The dependencies of the phase of eclipse of the white dwarf’s centre and the durations of the ascending and descending branches of the light curve on the binary system’s parameters were computed using the spherically symmetric approximation and the more ...
I. L. Andronov, K. D. Andrych
doaj   +1 more source

Polar stellar-spots and grazing planetary transits [PDF]

open access: yes, 2015
We assess whether there is a physically feasible explanation for the few discovered (nearly) grazing planetary transits through all ground- and space-based transit surveys.
J. J. G. Lima   +6 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Data set for article: Developing a Model for Curve-Fitting a Tree Stem’s Cross-Sectional Shape and Sapwood–Heartwood Transition in a Polar Diagram System Using Nonlinear Regression [PDF]

open access: yes
This data set contains the raw observed measurement of the circumference of a tree stem’s cross-section and its heartwood–sapwood transition, the transformation of rectangular coordinates (x, y) of the observed data points’ positions into polar ...
Bahtiar, E
core   +3 more sources

Compatibilizer Polarity Parameters as Tools for Predicting Organoclay Dispersion in Polyolefin Nanocomposites

open access: yesJournal of Nanotechnology, 2019
Nanocomposites give an innovative method to increase the mechanical, thermal, and barrier performance of polymers. However, properly dispersing the nanoparticles in the polymer matrix is often key in achieving high performance, especially in the case of ...
Marek Weltrowski, Patricia I. Dolez
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The topology of the generic polar curve and the Zariski invariant for branches of genus one

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
We study, for plane complex branches of genus one, the topological type of its generic polar curve, as a function of the semigroup of values and the Zariski invariant of the branch.
García Barroso Evelia R.   +2 more
doaj   +1 more source

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