Results 121 to 130 of about 79,547 (300)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Electronic and Polar Properties of Vanadate Compounds Stabilized by Epitaxial Strain [PDF]

, 2018
Recent experimental and computational studies have demonstrated pressure and epitaxial stabilization of polar PbVO3 phases with perovskite-derivative crystal structures.
Thomas Angsten (3264726), Lane W. Martin (1440505), Angsten, Thomas, Asta, Mark, Martin, Lane W, Mark Asta (1282041)   +5 more
core   +1 more source

Inequalities for the polar derivative of a polynomial

Journal of Approximation Theory, 1988
Let \(D_{\alpha}P(z)\) denote the polar differentiation of the polynomial \(P(z)\) of degree \(n\) with respect to the point \(\alpha\), i.e. \(D_{\alpha}P(z)=nP(z)+(\alpha -z)P'(z)\). In this paper several inequalities of Bernstein type for complex polynomials are generalized to the case of the polar differentiation.
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Designing Polar and Magnetic Oxides: Zn2FeTaO6 - in Search of Multiferroics [PDF]

, 2014
Polar oxides are technically of great interest but difficult to prepare. Our recent discoveries predicted that polar oxides can be synthesized in the corundum-derivative A2BB′O6 family with unusually small cations at the A-site and a d0 electron ...
Hemberger, Joachim, Croft, Mark C., Retuerto, Maria, Sarkar, Tapati, Walker, David, Greenblatt, Martha, Li, Man-Rong, Stephens, Peter W., Grams, Christoph P.   +8 more
core   +2 more sources

Palladium-catalyzed three-component radical-polar crossover carboamination of 1,3-dienes or allenes with diazo esters and amines

Beilstein Journal of Organic Chemistry
Herein, we report a visible-light-mediated palladium-catalyzed three-component radical-polar crossover carboamination of 1,3-dienes or allenes with diazo esters and amines, affording unsaturated γ- and ε-amino acid derivatives with diverse structures. In
Geng-Xin Liu, Xiao-Ting Jie, Ge-Jun Niu, Li-Sheng Yang, Xing-Lin Li, Jian Luo, Wen-Hao Hu   +6 more
doaj   +1 more source

Thermal behavior of Liquidambar orientalis mill wood before and after extraction processes

İstanbul Üniversitesi Orman Fakültesi Dergisi, 2017
The effect of extractives on the thermal behavior of Liquidambar orientalis Mill. (storax) wood is studied using thermogravimetric analysis (TGA). To evaluate the effects of polar and apolar extractives on the thermal behavior of wood, sawdust samples ...
Evren Terzi
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Thiofluorographene-hydrophilic graphene derivative with semiconducting and genosensing properties [PDF]

, 2015
We present the first example of covalent chemistry on fluorographene, enabling the attachment of –SH groups through nucleophilic substitution of fluorine in a polar solvent.
František Karlický, Adeline Huiling Loo, Čépe, Klára, Pumera, Martin, Veronika Urbanová, Martin Pumera, Bourlinos, Athanasios B., Kateřina Holá, Otyepka, Michal, Radek Zbořil, Karlický, František, Zbořil, Radek, Loo, Adeline Huiling, Athanasios B. Bourlinos, Urbanová, Veronika, Adriano Ambrosi, Ambrosi, Adriano, Klára Čépe, Holá, Kateřina, Michal Otyepka   +19 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source