Results 101 to 110 of about 314,028 (293)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

5-Azido-4-dimethylamino-1-methyl-1,2,4-triazolium Hexafluoridophosphate and Derivatives

open access: yesCrystals, 2016
5-Azido-4-(dimethylamino)-1-methyl-1,2,4-triazolium hexafluoridophosphate was synthesized from the corresponding 5-bromo compound with NaN3. Reaction with bicyclo[2.2.1]hept-2-ene yielded a tricyclic aziridine, addition of an N-heterocyclic carbene ...
Gerhard Laus   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Capacitance and compressibility of heterostructures with strong electronic correlations

open access: yes, 2017
Strong electronic correlations related to a repulsive local interaction suppress the electronic compressibility in a single-band model, and the capacitance of a corresponding metallic film is directly related to its electronic compressibility.
Frésard, Raymond   +2 more
core   +3 more sources

Polarized Infrared Spectra of Benzene Derivatives

open access: yesNippon kagaku zassi, 1964
m-ジニトロベンゼン,アセトアニリドおよびp-ジメトキシベンゼンの配向結晶をつくり,その偏光赤外スペクトルを測定した。面外水素振動およびその結合音の二色比より遷移モーメントの方向を計算し,その方向と結晶構造より期待される方向とを比較した。m-ジニトロベンゼンの場合,C2vの対称性を仮定して比較すると両者はよく一致する。一方,アセトアニリドの場合,ベンゼン核がC2vの対称性を持つとすると,両者はかなり異なった方向になるが,C2vの対称性を仮定すればよい一致を示す。
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effective Action of Spontaneously Broken Gauge Theories

open access: yes, 1996
The effective action of a Higgs theory should be gauge-invariant. However, the quantum and/or thermal contributions to the effective potential seem to be gauge-dependent, posing a problem for its physical interpretation.
Appelquist T.   +13 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Decadal Changes of the Reflected Solar Radiation and the Earth Energy Imbalance

open access: yesRemote Sensing, 2019
Decadal changes of the Reflected Solar Radiation (RSR) as measured by CERES from 2000 to 2018 are analysed. For both polar regions, changes of the clear-sky RSR correlate well with changes of the Sea Ice Extent. In the Arctic, sea ice is clearly melting,
Steven Dewitte   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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