Results 81 to 90 of about 314,028 (293)

Self-assembly and semiconductivity of an oligothiophene supergelator

Beilstein Journal of Organic Chemistry, 2010
A bis(trialkoxybenzamide)-functionalized quaterthiophene derivative was synthesized and its self-assembly properties in solution were studied. In non-polar solvents such as cyclohexane, this quaterthiophene π-system formed fibril aggregates with an H ...
Pampa Pratihar, Suhrit Ghosh, Vladimir Stepanenko, Sameer Patwardhan, Ferdinand C. Grozema, Laurens D. A. Siebbeles, Frank Würthner   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Application of M¨obius coordinate transformation in evaluating Newton’s integral

Contributions to Geophysics and Geodesy, 2011
We propose a numerical scheme which efficiently combines various existing methods of solving the Newton’s volume integral. It utilises the analytical solution of Newton’s integral for tesseroid in computing the near-zone contribution to gravitational ...
Robert TENZER, Vladislav GLADKIKH
doaj   +1 more source

Lorentz Group derivable from Polarization Optics

, 1997
5 pages, LaTeX file, no figures; presented at the 21st International Colloquium on Group Theoretical Methods in Physics (Goslar, Germany, July, 1996), to be published in the Proceedings. See also Phys. Lett. A, {\bf 219} 26-32 (1996)
Han, D., Kim, Y. S., Noz, M. E.
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Lifting quasianalytic mappings over invariants

, 2011
Let $\rho : G \to \operatorname{GL}(V)$ be a rational finite dimensional complex representation of a reductive linear algebraic group $G$, and let $\sigma_1,\sigma_n$ be a system of generators of the algebra of invariant polynomials $\mathbb{C}[V]^G$. We
Alekseevsky, Ambrosio, Armin Rainer, Bierstone, Bierstone, Bierstone, Bierstone, Dadok, De Giorgi, Hironaka, Kriegl, Kriegl, Kriegl, Kriegl, Kriegl, Losik, Luna, Montgomery, Palais, Procesi, Rainer, Schwarz, Thilliez   +22 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

INTEGRAL ANALOGUE OF TURÁN-TYPE INEQUALITIES CONCERNING THE POLAR DERIVATIVE OF A POLYNOMIAL

Ural Mathematical Journal
If \(w(\zeta)\) is a polynomial of degree $n$ with all its zeros in \(|\zeta|\leq \Delta, \Delta\geq 1\) and any real \(\gamma\geq 1\), Aziz proved the integral inequality [1] $$ \left\lbrace\int_{0}^{2\pi}\left|1+\Delta^ne^{i\theta}\right|^{\gamma}d ...
Mayanglambam Singhajit Singh, Barchand Chanam   +1 more
doaj   +1 more source

A Molecular Electron Density Theory Study of the Chemoselectivity, Regioselectivity, and Diastereofacial Selectivity in the Synthesis of an Anticancer Spiroisoxazoline derived from α-Santonin

Molecules, 2019
The [3 + 2] cycloaddition (32CA) reaction of an α-santonin derivative, which has an exocyclic C⁻C double bond, with p-bromophenyl nitrile oxide yielding only one spiroisoxazoline, has been studied within the molecular electron density theory ...
Luis R. Domingo, Mar Ríos-Gutiérrez, Nivedita Acharjee   +2 more
doaj   +1 more source