Results 81 to 90 of about 854,777 (264)

Polar bivalves are characterized by high antioxidant defences [PDF]

open access: yes, 2005
Inevitably, aerobic life leads to the formation of deleterious reactive oxygen species (ROS) which participate in biomolecule oxidation, hence augmenting biomolecule turnover.
Depledge, Michael H.   +3 more
core   +1 more source

Application of M¨obius coordinate transformation in evaluating Newton’s integral

open access: yesContributions to Geophysics and Geodesy, 2011
We propose a numerical scheme which efficiently combines various existing methods of solving the Newton’s volume integral. It utilises the analytical solution of Newton’s integral for tesseroid in computing the near-zone contribution to gravitational ...
Robert TENZER, Vladislav GLADKIKH
doaj   +1 more source

Assignments of NMR Spectral Data of a Novel Carbazole-Triazinoindole Based N-Acylhydrazone Derivative

open access: yesChinese Journal of Magnetic Resonance, 2020
N-acylhydrazone compounds have two isomers, E/cis and E/trans, in polar solvents. In this work, 1H and 13C nuclear magnetic resonance (NMR) signals, coupling constants (J), and the spatial structures of the two isomers (E/cis and E/trans) of a novel ...
LI Ying-jun   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

INTEGRAL ANALOGUE OF TURÁN-TYPE INEQUALITIES CONCERNING THE POLAR DERIVATIVE OF A POLYNOMIAL

open access: yesUral Mathematical Journal
If \(w(\zeta)\) is a polynomial of degree $n$ with all its zeros in \(|\zeta|\leq \Delta, \Delta\geq 1\) and any real \(\gamma\geq 1\), Aziz proved the integral inequality [1] $$ \left\lbrace\int_{0}^{2\pi}\left|1+\Delta^ne^{i\theta}\right|^{\gamma}d ...
Mayanglambam Singhajit Singh   +1 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Polar bears observed climbing steep slopes to graze on scurvy grass in Svalbard [PDF]

open access: yes, 2017
It is well known that polar bears feed on vegetation. Here, I report novel observations of polar bears grazing on polar scurvy grass (Cochlearia groenlandica) at the foot of a large seabird colony on a cliff on Spitsbergen, Svalbard, in the summers of ...
Stempniewicz, Lech
core  

The Chief Editor welcomes you to a free, green Polar Research [PDF]

open access: yes, 2010
Polar Research is now an open-access journal, freely available to anyone with a computer and connection to the internet. Now readers around the world will have free access to the latest scientific articles on climate, biodiversity, polar history and ...
Goldman, Helle
core   +1 more source

A Molecular Electron Density Theory Study of the Chemoselectivity, Regioselectivity, and Diastereofacial Selectivity in the Synthesis of an Anticancer Spiroisoxazoline derived from α-Santonin

open access: yesMolecules, 2019
The [3 + 2] cycloaddition (32CA) reaction of an α-santonin derivative, which has an exocyclic C⁻C double bond, with p-bromophenyl nitrile oxide yielding only one spiroisoxazoline, has been studied within the molecular electron density theory ...
Luis R. Domingo   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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