Results 91 to 100 of about 2,727,646 (335)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Self-assembly and semiconductivity of an oligothiophene supergelator

open access: yesBeilstein Journal of Organic Chemistry, 2010
A bis(trialkoxybenzamide)-functionalized quaterthiophene derivative was synthesized and its self-assembly properties in solution were studied. In non-polar solvents such as cyclohexane, this quaterthiophene π-system formed fibril aggregates with an H ...
Pampa Pratihar   +6 more
doaj   +1 more source

On the polar derivative of lacunary type polynomials

open access: yesCommunications Faculty Of Science University of Ankara Series A1Mathematics and Statistics
Let $p(z)=a_nz^n+\sum_{l=\nu}^na_{n-l}z^{n-l}$, where $1\leq \nu \leq n$, be a polynomial of degree $n$ having all its zeros in $|z|\leq k\leq 1$. For polar derivative $D_{\alpha}p(z)$, it is known that for each $|\alpha|\leq 1$ on $|z|=1$, \begin{align*} |D_{\alpha}p(z)|\leq \frac{n}{1+k^{\nu}}\Big\{(|\alpha|+k^{\nu})\|p\|_{\infty}-\frac{1 ...
Ahmad Motamednezhad, Fatemeh Mohammadi
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Review of LASHIPA: History of Large Scale Resource Exploitation in Polar Areas, edited by Louwrens Hacquebord

open access: yes, 2013
This collection of papers reflects the results of two separate but related research projects: the International Polar Year (IPY) project History of Large Scale Resource Exploitation in Polar Areas (LASHIPA) and a European Science Foundation Collaborative
Capelotti, P. J.
core   +1 more source

Assignments of NMR Spectral Data of a Novel Carbazole-Triazinoindole Based N-Acylhydrazone Derivative

open access: yesChinese Journal of Magnetic Resonance, 2020
N-acylhydrazone compounds have two isomers, E/cis and E/trans, in polar solvents. In this work, 1H and 13C nuclear magnetic resonance (NMR) signals, coupling constants (J), and the spatial structures of the two isomers (E/cis and E/trans) of a novel ...
LI Ying-jun   +5 more
doaj   +1 more source

Inequalities for the derivative and polar derivative of lacunary polynomials

open access: yesJournal of Mathematical Inequalities
Summary: In this paper, we study lacunary polynomials of degree \(n\) having \(s\)-fold zeros at the origin and the remaining zeros lying on or outside the boundary of a prescribed disk. This study in turns gives generalizations and improvements of some well-known results.
Arunrat, Nuttapong   +1 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Application of M¨obius coordinate transformation in evaluating Newton’s integral

open access: yesContributions to Geophysics and Geodesy, 2011
We propose a numerical scheme which efficiently combines various existing methods of solving the Newton’s volume integral. It utilises the analytical solution of Newton’s integral for tesseroid in computing the near-zone contribution to gravitational ...
Robert TENZER, Vladislav GLADKIKH
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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